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New Anti-Foot-and-Mouth Disease Vaccine Advances in Argentina

New Anti-Foot-and-Mouth Disease Vaccine Advances in Argentina

March 30, 2025 Catherine Williams - Chief Editor Health

New Vaccine Against Aphid Fever ‌Virus Under Advancement

Table of Contents

  • New Vaccine Against Aphid Fever ‌Virus Under Advancement
  • New⁣ Vaccine Against aphid Fever Virus: A ‍Q&A
    • what‍ is the new vaccine for Aphid fever virus‌ and how is it different?
    • Who is developing this new vaccine?
    • Why is a new vaccine needed?
    • How is ⁣the new vaccine produced?
    • What are the potential benefits of this new vaccine?
    • How does this new vaccine compare to the ⁢previous ⁤vaccine?
    • who made the previous vaccine?

Researchers are⁤ developing⁣ a novel vaccine against Aphid fever‌ virus using⁣ non-infective material during the production and ⁣distribution ‌process.

March 30, ‌2025

Researchers at the ​national Institute of ⁢agricultural‌ Technology (INTA), along⁤ with collaborators from‌ Canada’s NRCC and the ‌private company ‍Bioinnovo, ⁤are developing a first-of-its-kind ‍vaccine against Aphid fever virus. The key innovation is that the vaccine is produced without using any ⁢infective material.

INTA Laboratory
Laboratory setting at INTA. (Image: INTA)

According to ⁤a researcher, the existing vaccine against⁤ Aphid fever, while effective, has room for improvement. A‌ meaningful challenge is the ‌need for a type-3 safety plant, ‍a high-security⁢ laboratory, to prevent the virus from escaping.

The ⁤new vaccine is produced in mammalian cells‌ without ‍using infective material​ at any stage. Specialists believe this ⁢approach is safer ‍and more effective, and it can ​be implemented in existing plants without increasing internal security levels.

The researcher explained ⁤the process: What​ we did was searching the ⁤genes,that is,the‌ DNA sequences,which manufacture the‍ four proteins that generate the virus capsule and‍ put⁣ them into ⁤a mammalian ‌cell in collaboration with the NRCC of ⁤Canada,and we develop a line that,in its genome,retains those four proteins and we put together a ⁢false virus. Before a microscope ⁢is the ​same, but on the outside they are empty, although for the​ immune system they are virus, but with an empty box.

this innovation could substantially reduce production costs. ⁣ Thus,⁤ how to have‍ a plant (laboratory), it is indeed very expensive, if you could have a vaccine that has the same qualities but that no longer ‍requires that plant would imply a tremendous improvement.

SENASA
SENASA headquarters. (Image: ⁢SENASA)

The‍ researcher‌ added, What we did was develop​ a vaccine that ⁣is manufactured using the same infrastructure, that is, using the tachys ​where cells and system grow how the virus is purified,​ but that does not handle infectious ‍material.

The⁣ vaccine has been successfully tested in laboratory ⁤mice, cattle, and pigs. In all cases we had antibody titles ​equal to those obtained ‌with the conventional oily vaccine, the ‍researcher stated.

The ⁣researcher ‍also acknowledged the work⁤ of Scholeim Rivenson, who created the oily vaccine ‌against Aphid‌ fever. Rivenson’s⁤ work led to​ the ⁤eradication‍ of Aphid fever in Argentina⁤ after 120 ​years.⁣ He was also⁤ the creator and director of the veterinary ⁣Science Research Center.

New⁣ Vaccine Against aphid Fever Virus: A ‍Q&A

what‍ is the new vaccine for Aphid fever virus‌ and how is it different?

Researchers are ⁣developing⁤ a novel vaccine against Aphid fever virus, marking a⁣ significant advancement in⁣ veterinary medicine. The key innovation of this new vaccine is that ⁤it’s⁤ produced without using any ‍infectious material. This is ⁤a first-of-its-kind approach that could revolutionize how this disease is ‌combatted.

Who is developing this new vaccine?

The vaccine is being developed by researchers‌ at the National Institute of Agricultural Technology⁢ (INTA), in collaboration with Canada’s NRCC and the private‌ company Bioinnovo.

Why is a new vaccine needed?

While existing‍ vaccines against Aphid fever are effective,they have limitations. One significant challenge is the need for a high-security laboratory (type-3 safety plant) to prevent the virus from escaping. The new vaccine aims to ⁤overcome this challenge by being produced ‍in a safer manner.

How is ⁣the new vaccine produced?

The new‌ vaccine is produced​ in mammalian cells without ‌using infectious material at any stage. This safer approach can be implemented in existing plants ‍without increasing internal security levels.

Here’s a breakdown of the⁣ production process:

The researchers identified the genes, or DNA sequences, that create the four proteins forming the virus capsule.

these genes are inserted⁣ into mammalian cells.

⁣ A cell line is‌ developed that contains​ these four proteins.

This process creates a “false ⁤virus” that,although appearing identical to the actual virus under a microscope,is empty and non-infectious.

The immune system recognizes⁤ it and reacts‌ as if it were the real virus.

What are the potential benefits of this new vaccine?

The new vaccine​ may provide several advantages:

Enhanced Safety: ‌ The ‍production method eliminates the need for high-security laboratories,thus minimizing the risk of virus ‌escape.

Cost Reduction: Eliminating the need for a type-3 safety plant could significantly reduce production costs.

Compatibility: ⁤ The vaccine⁢ can be manufactured using existing infrastructure.

* Effectiveness: Laboratory tests​ on mice,⁢ cattle, ​and pigs have shown that the new vaccine⁣ generates⁣ antibody levels equivalent to those provided by conventional, existing vaccines.

How does this new vaccine compare to the ⁢previous ⁤vaccine?

Here’s a comparison of the new vaccine against Aphid fever virus with the previous one:

| Feature | New Vaccine ‍ ⁤ ‌ ⁤ ‌ ​ ⁢ ​| Previous Vaccine ⁣ ​ ​ ‍ ‍ ⁤ ⁢ |

| ​:————– | :———————————————————————– | :———————————————– ⁢|

| Production ‌Material | No infectious material |‌ Infectious material |

| Safety Requirements | Lower (existing plants​ can be used) | ⁢High (requires a type-3 safety plant) |

| Production Costs | Potentially lower ⁣ ‌ ‌ ⁤ ‌ ‌ ‍ ⁤ | can Be High ⁣ ⁢ ‌ ‍ ​ ‍ ⁢ |

| Antibody Response | Equivalent to previous vaccine​ ‍ ‍ ⁤ | Effective ⁢ ​‌ ​ ⁤ |

who made the previous vaccine?

The⁢ previous‍ vaccine was developed ​by scholeim rivenson, ‍whose work led⁣ to the eradication of Aphid fever in argentina after 120 years. He was ​also the creator ‌and director ​of the Veterinary ⁣Science Research Center.

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