New Cardiovascular Risk Score for Women
New Risk Score Accurately Predicts Heart Risks in Women
Study Finds Integrating Clinical Data and Imaging Improves Cardiovascular Risk Assessment
(New York, NY) December 18, 2024 – A groundbreaking new risk score is showing promise in accurately predicting the risk of major adverse cardiovascular events in women. Published in the journal Radiology: Cardiothoracic Imaging, the study highlights the benefits of a novel approach that combines clinical variables wiht imaging data.
Heart disease remains the leading cause of death for women worldwide, according to the Centers for disease Control and Prevention. While men are more frequently affected, experts say women are often underrepresented in cardiovascular research, leading to potential gaps in understanding and treatment.”Women are frequently underrepresented in research studies and, in certain specific cases, may even be excluded,” says lead study author Dr. Guillermo Romero-Farina, a cardiologist and principal investigator at Vall d’Hebron University Hospital in Barcelona, spain. “Risk stratification in women is especially crucial because the clinical presentation of coronary artery disease can differ from men and is often atypical.”
The study, a retrospective analysis of data from 2,226 women aged 40 to 93, utilized myocardial perfusion imaging via SPECT and tracked patients for an average of four years.Researchers developed the Coronary Risk score for Women (CORSWO) using eight variables to calculate each patient’s risk of cardiac events and categorize them into four risk levels: low, moderate, high, and very high.

“by grouping patients into different risk levels, physicians can better focus resources and treatments on those who need them most,” explains Dr. Romero-Farina.
The CORSWO model accurately predicted major adverse cardiovascular events in women classified as high and very high risk, outperforming other existing risk models.
This new approach, which integrates clinical data, exercise-related factors, and imaging-based facts, is crucial for accurately calculating heart risk in women.
“This approach helps us detect potential heart problems earlier, particularly serious events like heart attacks and sudden cardiac death, which are the events cardiologists strive to prevent,” Dr. Romero-Farina concludes.
A New Era for Women’s Heart Health: Predicting Risk with CORSWO
Q: Dr. Romero-Farina, your new study in Radiology: Cardiothoracic Imaging has generated a lot of excitement. Can you explain what makes the Coronary Risk Score for Women (CORSWO) so groundbreaking?
A: For far too long, women’s heart health has been overlooked in research. This has contributed too a disparity in our understanding and treatment of cardiovascular disease in women. CORSWO is different. our model not only incorporates traditional clinical risk factors, but it also integrates critical data from myocardial perfusion imaging and exercise-related factors.
Q: Why is this combination of data points so crucial for assessing heart risk in women specifically?
A: Women often present with atypical symptoms of heart disease, making diagnosis more challenging. Moreover, the clinical presentation can differ significantly from men. By combining clinical data with imaging-based insights,CORSWO provides a more nuanced and accurate picture of a woman’s individual risk.
Q: How does CORSWO impact treatment and prevention strategies?
A: CORSWO categorizes patients into four distinct risk levels: low, moderate, high, and very high. This allows physicians to prioritize resources and tailor treatment plans based on an individual’s risk profile. For those at higher risk, early intervention and lifestyle modifications can be crucial for prevention.
Q: What were the key findings of your study in terms of CORSWO’s accuracy in predicting cardiovascular events?
A: Our study showed that CORSWO was especially effective in predicting major adverse cardiovascular events in women classified as high and very high risk. It outperformed existing risk models, demonstrating its potential to significantly improve risk stratification and patient care.
Q: What does this meen for the future of women’s heart health?
A: CORSWO represents a significant step forward in our ability to identify women at risk for heart disease and provide them with the personalized care they need. By detecting potential problems earlier, we can prevent serious events like heart attacks and sudden cardiac death. This is a victory for women’s health and a testament to the power of research and innovation.
