New Research Findings
- Studie: Acht Monate nach Cannabis-Teillegalisierung keine Auswirkungen festzustellen | Impfstoffkandidat gegen MERS zeigt langanhaltende Immunantwort | Nicht-invasive Diagnostik der Tuberkulose aus Atemschutzmasken | Schon moderate Hitze belastet chronisch...
- An experimental vaccine candidate against Middle East Respiratory Syndrome (MERS) developed by scientists at the University Medical Center Hamburg-Eppendorf (UKE) triggers a stable and functional immune response in...
- The vaccine candidate MVA-MERS-S, which is based on an attenuated smallpox virus, was investigated.
Teilen:
26.01.2026 16:00
Neues aus der Forschung
Table of Contents
Studie: Acht Monate nach Cannabis-Teillegalisierung keine Auswirkungen festzustellen | Impfstoffkandidat gegen MERS zeigt langanhaltende Immunantwort | Nicht-invasive Diagnostik der Tuberkulose aus Atemschutzmasken | Schon moderate Hitze belastet chronisch erkrankte Menschen | Regulation super-schneller signale bei der Aktivierung von T-Lymphocyten aufgeklärt
An experimental vaccine candidate against Middle East Respiratory Syndrome (MERS) developed by scientists at the University Medical Center Hamburg-Eppendorf (UKE) triggers a stable and functional immune response in humans even two years after a booster vaccination. This is the result of a long-term clinical study conducted by an international research team from the German Center for Infection Research (DZIF) led by the UKE and funded by the DZIF and the Coalition for Epidemic Preparedness Innovations (CEPI). The researchers have published their findings in the journal Nature Communications.
The vaccine candidate MVA-MERS-S, which is based on an attenuated smallpox virus, was investigated. MERS causes severe respiratory diseases with a high mortality rate of up to 36 percent. Although infections in humans have been rare so far,the virus is considered a potential threat for future outbreaks.MERS is on the WHO list of priority pathogens for which vaccines and therapies are urgently needed.
In addition to the UKE, the study involved the Institute for Virology at Charité, the Institute for Virology at Philipps University Marburg, and the Department of Viroscience at Erasmus Medical Centre in Rotterdam (Netherlands). It was carried out in cooperation with the Collaborative Research Centre 1648 “Emerging Viruses: Structure, Pathogenesis and Immunity,” which is led by the UKE.
Publication: Mayer et al. Two-year persistence of MERS-CoV-specific antibody and T cell responses after MVA-MERS-S vaccination in healthy adults. Nature Communications.2026.
DOI: https://doi.org/10.1038/s41467-025-68248-5
Contact for inquiries: Prof. Dr. Marylyn Addo,Institute for Infection research and Vaccine Growth
A prospective study by scientists at the university Medical Center Hamburg-Eppendorf (UKE) shows that so-called Face-Mask Sampling (FMS) can be a promising,non-invasive addition to the current diagnostics for pulmonary tuberculosis. In FMS, the DNA of the tuberculosis pathogen Mycobacterium tuberculosis is directly extracted from the exhaled air of patients. To do this, patients wear special masks that collect exhaled pathogen particles.
Association between psychosocial factors and adverse effects of light-to-moderate ambient heat in patients with chronic diseases: Results of the prospective cohort study CLIMATE-II.
Researchers have linked weather data to health outcomes. The results were published in the journal BMC Medicine.
Publication: Schäfer et al., Association between psychosocial factors and adverse effects of light-to-moderate ambient heat in patients with chronic diseases: Results of the prospective cohort study CLIMATE-II., BMC Medicine. 2026.
DOI: https://doi.org/10.1186/s12916-026-04622-4
Contact for inquiries: Priv.-doz. Dr. Ingmar Schäfer, Institute and Polyclinic for General Practice
Regulation of super-fast signals during T-lymphocyte activation clarified
After researchers at the University Medical Center Hamburg-Eppendorf (UKE) had already described super-fast signals through calcium ions below the plasma membrane of T-lymphocytes, they have now succeeded in elucidating the regulation of the involved enzymes and ion channels. They found that the key enzyme (DUOX2) is activated by several self-reliant processes and thus acts as a biological coincidence detector. “The newly identified signaling pathway opens up promising approaches for new therapies for autoimmune diseases,” explains study leader Prof. Dr. Dr. Andreas H.Guse, director of the Institute for Biochemistry and Molecular Cell Biology at the UKE. In autoimmune diseases, various immune cells are activated incorrectly. Therefore, a precise molecular understanding of the biochemical and cell biological processes of the activation of these cells has great translational significance in the development of new therapeutic approaches. In addition to the UKE, the study also involved the University of Oslo, the Medical University of Innsbruck, the University of Hamburg, the University of Bonn, the Université libre de Bruxelles, the Ludwig-Maximilians-University Munich, and the University of Göttingen. It was funded by the Collaborative Research Center 1328 on the topic of “Adenine nucleotides in immunity and inflammation,” which is led by the UKE.
publication: Kai J. Winterberg et al. Multiple signaling events are required for NAADP synthesis by DUOX2 and formation of Ca2+ microdomains to initiate T cell activation. Science Signal. 2026.
DOI: https://doi.org/10.1126/scisignal.adp4326
Contact for inquiries: Prof. Dr. Dr. Andreas H. Guse, Institute for Biochemistry and Molecular Cell Biology
Funding for collaborative research
IDW-Online Search Results – Loading Status
the IDW-Online website is currently displaying a loading indicator, suggesting a search query is in progress or content is being dynamically generated.
As of january 26, 2026, at 15:16:52, the page remains in a loading state. There are no new developments reported regarding the functionality of the IDW-Online website.
about IDW-Online
IDW-Online (https://idw-online.de/) is a German-language press release distribution service and science communication platform operated by the information Service Science (idw) at the Technical University of Braunschweig.
IDW-online primarily serves to disseminate research news and press releases from German universities and research institutions.
Exmaple: In 2023, IDW-Online distributed over 10,000 press releases covering a wide range of scientific disciplines, according to IDW’s own reporting.
Technical Status & Potential Issues
The presence of a loading indicator can be attributed to several factors, including server response time, complex search queries, or issues with dynamic content loading.
Users experiencing prolonged loading times may consider checking their internet connection or attempting the search again later.
As of January 26, 2026, there are no widespread reports of outages or technical difficulties affecting IDW-Online, according to Down For Everyone Or Just Me (checked January 26,2026).