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PFAS Gut Bacteria: Absorption and Elimination

July 13, 2025 Jennifer Chen Health
News Context
At a glance
Original source: theguardian.com

Microbes Offer Hope in Fight Against “Forever Chemicals”

Table of Contents

  • Microbes Offer Hope in Fight Against “Forever Chemicals”
    • The Microbial defense Mechanism
      • Targeting Long-Chain PFAS
    • From Lab to probiotic: The future of PFAS Remediation
      • A Call for Continued Action

New research explores how tiny organisms can help the body expel harmful PFAS compounds.

Scientists are exploring a groundbreaking new approach to combatting the pervasive threat of PFAS, frequently enough dubbed “forever chemicals.” Research suggests that certain microbes possess a natural defense mechanism that could help the human body eliminate these persistent pollutants.

The Microbial defense Mechanism

Dr.Ashley Lindell, a lead researcher in the field, explained that while the exact mechanisms are still being understood, thereS a strong suspicion that microbes develop specialized pumps. “These are developed by microbes to expel other contaminants, drugs or antibiotics,” Lindell stated, hinting at a potential biological solution to a widespread environmental and health problem.

Targeting Long-Chain PFAS

The focus of this research is on “long-chain” PFAS, which are considered more dangerous due to their larger molecular structure and tendency to remain in the body for extended periods. In contrast, “short-chain” PFAS are generally discharged more efficiently through urine because they are more water-soluble.The study highlighted the effectiveness of these microbial mechanisms against some of the most common and concerning long-chain PFAS, such as PFOA and PFNA. The microbes demonstrated extraordinary expulsion rates, removing up to 58% of PFOA and a remarkable 74% of PFNA.

From Lab to probiotic: The future of PFAS Remediation

Building on these promising findings, Lindell and her fellow researchers have established a company named Cambiotics.Their ambitious goal is to develop a probiotic supplement based on their discoveries, offering a potential dietary intervention for individuals exposed to PFAS.The team is planning to move forward with human studies to validate the efficacy and safety of this probiotic approach.

A Call for Continued Action

While the development of a probiotic offers a beacon of hope, dr. Lindell emphasized that it is indeed not a silver bullet for the entire PFAS crisis. “This should not be used as an excuse to downplay other lasting solutions or to not address the bigger PFAS problem,” she cautioned.The research underscores the importance of a multi-faceted approach, combining scientific innovation with broader environmental policies to tackle the pervasive issue of forever chemicals.

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