POAG & Mental Health: New Research Findings
New research reveals a significant connection: primary open-angle glaucoma (POAG) may impact mental health. The study, published in JAMA Ophthalmology, found that POAG patients experienced a greater decline in mental health scores after their diagnosis. Researchers compared mental health assessments using the Visual Function Questionnaire-25 (VFQ) to evaluate the impact of POAG. The findings spotlight the necessity of evaluating mental well-being in those wiht POAG,urging further investigation into how glaucoma affects mental health and how to best support patients. While the study notes specific limitations, it emphasizes the need for more research on the link between primary open-angle glaucoma and mental health. News Directory 3 keeps you informed.Discover what’s next in glaucoma care.
Glaucoma Diagnosis May Impact Mental Health, Study Finds
Updated June 11, 2025
A recent study in JAMA Ophthalmology suggests a potential connection between a diagnosis of primary open-angle glaucoma (POAG) and reduced mental health scores. Researchers found that individuals diagnosed with POAG experienced a greater decrease in mental health scores compared to those without the condition. The research highlights the importance of considering mental health in glaucoma patients.
The study, drawing data from the Ocular Hypertension Treatment Study (OHTS), assessed participants’ mental health using the Visual Function Questionnaire-25 (VFQ). The goal was to evaluate the mental health of individuals with early POAG both before and after their diagnosis, in comparison to a control group. participants completed the VFQ every two years between 2001 and 2008.
The study included 50 POAG patients and 100 without.before diagnosis, the POAG group had a mean VFQ mental health score of 94.5, which dropped to 88.0 post-diagnosis. The control group saw a smaller change, from 93.3 to 92.6. This indicates a potential association between a POAG diagnosis and a decline in mental health.

Researchers acknowledged limitations, including the small sample size and the two-year intervals between mental health surveys, which might have missed immediate effects of the diagnosis. The VFQ also wasn’t designed for in-depth mental health assessments. The study underscores the need for further investigation into the relationship between primary open-angle glaucoma, mental health, and overall patient well-being.
“Further studies are needed to confirm the association between POAG diagnosis and decrease in mental health score and to develop strategies to inform patients about their POAG diagnosis without producing undue distress, anxiety, and depression,” the researchers concluded.
What’s next
Future research shoudl focus on confirming the link between POAG diagnosis and mental health, as well as developing strategies to support patients’ mental well-being following a diagnosis of glaucoma. Addressing mental health is crucial for providing comprehensive care to individuals with POAG.
