Prenatal Cannabis Exposure: Brain Development Effects
- London (IT Boltwise) - A new study illuminates the potential effects of prenatal exposure to cannabis on brain development and psychotic symptoms in young people.
- Prenatal exposure to cannabis could have long -term effects on brain development and the occurrence of psychotic symptoms in young people.
- However, psychotic experiences that represent subclinical symptoms are similar to characteristics of psychosis, but occur in people who do not meet the diagnostic criteria for a psychotic disorder.
London (IT Boltwise) – A new study illuminates the potential effects of prenatal exposure to cannabis on brain development and psychotic symptoms in young people.
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Prenatal exposure to cannabis could have long -term effects on brain development and the occurrence of psychotic symptoms in young people. A comprehensive analysis of data from the Adolescent Brain and Cognitive Development (ABCD) study shows that children who were exposed to cannabis in the womb report more psychotic experiences. These experiences are associated with reduced neuronal activation in the brain reward system, especially in the striatum, which plays a key role in motivation and reward expectation.
However, psychotic experiences that represent subclinical symptoms are similar to characteristics of psychosis, but occur in people who do not meet the diagnostic criteria for a psychotic disorder. Such experiences can include hearing voices, unusual beliefs or paranoid thoughts. During adolescence, these symptoms are relatively common, with many young people at least of all experiencing such experiences.
Although psychotic experiences are temporary in most cases, frequent or stressful experiences can increase the risk of future psychiatric diseases such as schizophrenia, depression and fear. The study, led by Carolyn M. Amir and Carrie E. Tharden, examined the hypothesis that psychotic experiences are associated with a reduced neuronal activity in reward -related brain regions, especially among young people who were exposed to prenatal cannabis.
The researchers used functional MRI scans to measure the neural reactions during reward anticipation. The results showed that children with prenatal cannabis exposure reported more psychotic experiences and had lower activation in the striatum during reward anticipation. This reduced activation could be a way to increase the risk of psychotic experiences through prenatal cannabis exposure.
In addition, psychotic experiences were associated with higher reward motivations and impulsiveness, especially among young people with prenatal cannabis exposure. This group achieved higher values in reward drive, reward reactivity and various dimensions of impulsiveness. The study underlines the need for further research to understand the long-term effects of prenatal cannabis exposure to mental health.
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