Sugar & Artificial Sweeteners Linked to MASLD Risk

hear’s a breakdown of the key findings from the provided text:

Study Overview:

* Type: prospective cohort study using data from the UK Biobank.
* participants: 103,251 individuals without pre-existing liver disease.
* ‍ Duration: Median follow-up of 10.3 ⁣years.
* ⁤ Focus: Investigated the link between consumption of Sugar-Sweetened Beverages⁤ (SSBs) and Low/Non-Sugar-sweetened Beverages (LNSSBs) and the risk of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) and liver-related mortality.

Key Findings:

* ⁢ MASLD ‍Risk:

* High intake of both LNSSBs ⁤(>330g/day) and SSBs (>330g/day)⁤ was associated⁣ with a significantly increased risk of developing MASLD (hazard ratio⁤ of 1.597 for LNSSBs and 1.502 for SSBs).
*⁣ Liver-Related Mortality:

⁢ * LNSSB consumption increased the risk of liver-related mortality in a dose-dependent manner.
‍ * No significant association was ⁢found between SSB consumption and liver-related mortality.
* Liver Fat content:

‍ ⁤ * ‍ ‍Both SSB and LNSSB ⁤consumption were positively associated with liver fat content.
* ⁣ Substitution⁢ Analysis:

* Replacing 330g/day of either ‍beverage⁤ with water reduced MASLD risk (14.7% for SSBs, 13.5% for LNSSBs).
* ⁢ Substituting between LNSSBs and ssbs did not change the risk.
* ⁢ Vital Quote: The study suggests even moderate LNSSB intake (like ⁤one can ⁢per day)‍ is linked to a higher risk of MASLD, challenging the perception ⁤that these drinks are harmless.

In essence, the study suggests that both sugary drinks and ⁣artificially sweetened drinks can ⁤negatively impact liver health, with LNSSBs perhaps posing a greater risk for liver-related mortality.