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Syphilis in Pregnancy: Rates Soar to 1990s Highs | CDC Report

Syphilis in Pregnancy: Rates Soar to 1990s Highs | CDC Report

March 8, 2026 Dr. Jennifer Chen Health

Maternal syphilis rates in the United States are the highest they’ve been in decades, according to recently released data. A new report from the National Center for Health Statistics (NCHS) indicates a 2016 to 2022 increase of 222% in the rate of syphilis among pregnant women, followed by another 28% rise between 2022 and 2024. This concerning trend underscores a critical gap in preventative care, as syphilis is readily treatable, even during pregnancy, if detected.

Syphilis is a sexually transmitted infection (STI) caused by the bacterium Treponema pallidum. Transmission occurs through vaginal, anal, or oral sex, and crucially, can also be passed from a mother to her infant during pregnancy or childbirth, resulting in congenital syphilis. Congenital syphilis carries severe risks, including miscarriage, stillbirth, and infant death. Infants born with the infection can experience lifelong health complications.

Early-stage syphilis often presents with no noticeable symptoms, making testing the primary means of diagnosis for many individuals. A simple blood test can accurately detect the infection. Fortunately, routine prenatal care typically includes syphilis screening at the first pregnancy check-up, and many states mandate this initial screening. Some states extend testing to the third trimester and at the time of delivery, with healthcare providers often recommending these additional tests even where not legally required.

However, access to prenatal care remains a significant barrier for many in the U.S. Financial constraints, such as lack of insurance or high healthcare deductibles, can prevent women from seeking timely care. Logistical challenges, including transportation difficulties and time off from work, also contribute to the problem. The closure of maternity wards in rural hospitals and a general lack of pregnancy care providers in rural areas further exacerbate the issue. Studies indicate that approximately 35% of women of reproductive age (typically defined as 15 to 44) in the United States reside in areas with limited access to maternal health services.

These disparities disproportionately affect low-income women, women of color, and those living in rural communities. The Centers for Disease Control and Prevention (CDC) has noted that these inequities contribute to the increased rates of syphilis and congenital syphilis. According to the CDC, racial and ethnic minorities are most disproportionately affected due to “long standing social inequities that often lead to health inequalities.”

The recent surge in syphilis cases isn’t limited to maternal infections. Data from 2024 shows a significant overall increase in syphilis rates across all age groups and regions of the country. The CDC reported nearly 80% increase in cases between 2018 and 2022. This broader increase is likely driven by a complex interplay of factors, including increases in substance abuse linked to risky sexual behavior, decreased condom use, and reductions in access to STI services at the state and local levels.

The consequences of untreated congenital syphilis are particularly devastating. In 2022, 3,755 cases of babies born with syphilis were reported in the U.S., a staggering 937% increase over the past decade. This resulted in 282 stillbirths and infant deaths in 2022 alone. These numbers highlight the urgent need for improved screening and treatment programs.

The CDC emphasizes that a significant proportion of congenital syphilis cases – nearly 90% – are preventable with adequate testing and treatment of pregnant women. This underscores the importance of expanding access to prenatal care, particularly in underserved communities, and ensuring that all pregnant women are screened for syphilis at appropriate intervals.

The rise in congenital syphilis is a “direct result of untested and untreated mothers,” according to maternal-fetal medicine physician Dr. Irene Stafford of UTHealth Houston. She explains that syphilis is “particularly pathogenic, it’s particularly infectious to the fetus, and rates are skyrocketing.” The risk of transmission from mother to fetus is approximately 70% in the early stages of infection and remains substantial throughout pregnancy.

Addressing this public health crisis requires a multi-faceted approach. Increased funding for STI prevention and control programs, expanded access to affordable healthcare, and targeted outreach to vulnerable populations are all essential steps. Continued monitoring of syphilis rates and ongoing research into effective prevention strategies are also crucial. The CDC provides resources and guidance for healthcare providers and the public on syphilis prevention, testing, and treatment.

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