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TrumpRx: New Platform Offers Cash Prices on Prescription Drugs in 2026

by Dr. Jennifer Chen

On , President Donald Trump unveiled TrumpRx.gov, a new platform intended to help uninsured patients access lower prices on prescription drugs. The website aggregates direct-to-consumer (DTC) purchasing platforms for over 40 key medications, including those used for fertility treatments and weight management, with plans for expansion. Unlike a traditional pharmacy, TrumpRx does not directly sell medications. Instead, it functions as a search tool, directing patients to manufacturer coupons or DTC platforms where they can potentially save on their prescriptions.

The platform is designed for individuals without insurance coverage who pay cash for their medications. A disclaimer on the website emphasizes that the listed prices are for out-of-pocket payments and encourages insured patients to compare these prices with their insurance copays, as the latter may be lower.

Which Drugs Are Included on TrumpRx?

Currently, TrumpRx features a range of medications, including oral and injectable semaglutide (marketed as Wegovy and Ozempic by Novo Nordisk), tirzepatide (Zepbound, Eli Lilly and Company), follitropin alfa injection (Gonal-F, EMD Serono), cetrorelix acetate for injection (Cetrotide, EMD Serono), and insulin lispro (Humalog, Eli Lilly and Company).

The availability of discounts varies by medication. For some, like oral semaglutide, the platform provides coupons redeemable at local pharmacies nationwide. Patients can locate participating pharmacies through the website and present their coupon at the time of purchase. Other medications, such as albuterol/budesonide (Airsupra, AstraZeneca), tirzepatide (Zepbound, Eli Lilly and Company), and dapagliflozin/metformin (Xigduo XR, AstraZeneca), require direct purchase through the manufacturer’s website via a provided link.

Reactions to the Announcement

The launch of TrumpRx has elicited mixed reactions. Some organizations have praised the initiative as a potential step toward greater affordability for prescription drugs. However, the extent of actual savings remains unclear.

“Today marks a monumental step in transforming drug pricing and making prescription drugs more affordable for the American people, particularly for those without insurance,” said Carl Schmid, executive director of the HIV+Hepatitis Policy Institute, in a news release. “For those who do have insurance, TrumpRx may not always be the best option.”

Critics, including some Democrats, have expressed concerns that the platform may create confusion for patients and primarily serve to benefit the former president. Senator Ron Wyden (D-Ore), Ranking Member of the Senate Finance Committee, stated, “TrumpRx is nothing more than a glorified coupon book, and it will advance the Republican agenda to undermine affordable health care for American families.” He argued that patients should not have to navigate additional hurdles to access affordable medications and emphasized the need for lower prices at the point of sale, regardless of coupon usage.

The Trump Administration has framed TrumpRx as a result of agreements struck with pharmaceutical companies, encouraging them to launch DTC purchasing platforms for uninsured patients. This initiative is rooted in the concept of “Most Favored Nation” pricing, which aims to align drug prices in the United States with those found in other high-income countries. The administration highlights potential savings on medications for conditions like infertility and obesity.

However, experts note that prices for some of these medications, particularly glucagon-like peptide-1 (GLP-1) medications used for weight loss, have already been trending downward. Many of the drugs featured on TrumpRx are already covered by insurance plans, and some have generic alternatives available.

As TrumpRx continues to develop, its ultimate impact on drug affordability remains to be seen. While the platform may offer valuable savings for some uninsured patients, particularly those requiring expensive or difficult-to-access therapies, it adds another layer of complexity to the existing drug pricing landscape. The success of TrumpRx will depend on manufacturers’ continued expansion of their DTC programs and the administration’s ability to effectively promote the platform and demonstrate tangible benefits for patients, providers, and policymakers. It remains to be determined whether TrumpRx will deliver substantial improvements in drug affordability or simply reorganize existing options without addressing the fundamental drivers of high prescription drug costs.

REFERENCES
1. TrumpRx. Accessed . https://trumprx.gov/
2. Robbins R, Sanger-Katz M. Trump’s online drugstore opens for business. The New York Times. Published . Accessed . https://www.nytimes.com/2026/02/05/health/trumprx-online-drugstore-prices.html
3. Hutzler A, Wang S, Neporent L, Stoddart M. Trump unveils TrumpRx website he says will help Americans buy lower-priced prescription drugs. ABC News. Last Updated . Accessed . https://abcnews.go.com/Politics/trump-unveil-trumprx-website-americans-buy-lower-priced/story?id=129895605
4. President Trump launches TrumpRx.gov, delivering massive, immediate savings to millions of Americans. The White House. News Release. Released . Accessed . https://www.whitehouse.gov/articles/2026/02/president-trump-launches-trumprx-gov-delivering-massive-immediate-savings-to-millions-of-americans/

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