Vikings vs Chargers Predictions: NFL Thursday Night Football Picks

October 23, 2025 David Thompson - Sports Editor Sports

Okay, here’s a breakdown of the provided text, focusing on betting information and predictions for the Vikings vs.chargers game.

Key Takeaways & Betting Opportunities:

* Game: Vikings vs. Chargers
* Date/Time: Thursday, October 23, 2025, 8:15 PM ET
* Location: SoFi Stadium, Inglewood, CA

1. Single Game Parlays (SGPs):

* SGP 1 (+595):

* Vikings Moneyline (+145)
* Both Teams Score 15+ Points (-195)
* Carson Wentz Over 222.5 passing Yards (-114)
* SGP 2 (“Justin Jefferson Airplane”) (+1240):

* Vikings Moneyline (+145)
* Both Teams Score 15+ Points (-195)
* Carson Wentz Over 222.5 Passing Yards (-114)
* Justin Jefferson Over 75.5 Receiving Yards (-118)

2. game Predictions & Analysis:

* Moneyline: The analysis leans towards Vikings to win (+155). The Chargers are described as having “major red flags” and the Vikings have been responding well to losses.
* Spread: The analysis suggests taking Vikings +3 (-110). The Vikings are considered to have an edge on both sides of the ball.
* Over/Under: The prediction is Over 44.5 (-110). Both teams have struggling defenses and aggressive passing attacks.
* Justin Jefferson: Jefferson is highlighted as a key player, with recent strong performances and a high target share.

3.Odds:

* Spread: Vikings +3 (-110) / Chargers -4 (-110)
* Moneyline: Vikings +155 / Chargers -185
* Over/Under: Over 44.5 (-110) / Under 44.5 (-110)

4.Betting Trend:

* The Chargers have gone Over the 3rd Quarter Total in 15 of their last 19 games (45% ROI).

In summary: The analysis is bullish on the Vikings, suggesting they are a good upset pick.The Over on the total points is also favored. The SGPs offer higher payouts, with the “Justin Jefferson Airplane” SGP being the most lucrative but also the riskiest.