Vitamin D & Aging: Does Supplementation Slow Biological Age?
- Vitamin D supplementation may play a role in maintaining telomere length, according to a new randomized controlled trial.Telomeres, protective caps on the ends of chromosomes, naturally shorten with...
- The VITAL study, a large-scale, long-term trial, suggests that vitamin D supplements could protect telomeres.
- Telomere shortening is a natural part of aging, increasing the risk of age-related diseases.
Vitamin D Supplements Linked to Longer Telomeres, Study Finds
Updated May 29, 2025
Vitamin D supplementation may play a role in maintaining telomere length, according to a new randomized controlled trial.Telomeres, protective caps on the ends of chromosomes, naturally shorten with age and are associated with age-related diseases.
The VITAL study, a large-scale, long-term trial, suggests that vitamin D supplements could protect telomeres. JoAnn Manson, MD, principal investigator of VITAL and chief of the Division of Preventive Medicine at brigham and Women’s Hospital, noted the findings are of interest because VITAL previously demonstrated vitamin D’s benefits in reducing inflammation and risks of chronic diseases.
Telomere shortening is a natural part of aging, increasing the risk of age-related diseases. The VITAL Telomere sub-study included 1,054 participants, tracking telomere length over four years.
The research indicated that vitamin D3 supplements considerably reduced telomere shortening compared to a placebo, effectively preventing nearly three years of aging. Omega 3 fatty acid supplementation showed no notable impact on telomere length.
“Our findings suggest that targeted vitamin D supplementation may be a promising strategy to counter a biological aging process, although further research is warranted,” said Haidong Zhu, PhD, first author of the report and a molecular geneticist at the Medical College of Georgia, Augusta University.
What’s next
further research is needed to confirm these findings and explore the optimal dosage and duration of vitamin D supplementation for telomere maintenance and overall health.
