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HPV Vaccine Effectiveness Against Cancer: Research on Millions of Patients

by Dr. Jennifer Chen

Confirmations of teh efficacy and safety ​of the ‍vaccine against cervical cancer (and not only). the HPV virus is also responsible for 60-70% ‍of oral carcinomas (whose cases are increasing)

8mila ‌tumori ‌ogni anni in Italia dovuti al virus

Quella ‌da Papillomavirus umano (HPV) è l’infezione sessualmente trasmessa più diffusa in entrambi ‍i sessi. Alcuni ‍dei⁤ 200 ceppi di virus Hpv,che‌ si ​trasmette per via sessuale, hanno un ruolo chiave nell’insorgenza sia​ di tumori‌ che di lesioni precancerose​ (condilomi genitali) maschili ⁤e femminili,mentre altri ⁤ceppi del virus sono innocui.
Secondo le stime più recenti in Italia ogni‌ anno sono quasi 8mila i casi di cancro⁤ dovuti⁤ all’HPV
Le nuove revisioni confermano che la vaccinazione contro l’HPV può prevenire lo sviluppo della maggior parte di questi tumori, soprattutto se somministrata prima  dell’inizio dell’attività sessuale (ma‌ è

Utilità e sicurezza del vaccino: ulteriori nuove conferme

The frist Cochrane Library review ‍included 60 studies with 157,414 participants. The authors found that all‌ HPV vaccines were effective in preventing infections that can led to cancer ⁢ and other HPV-related diseases, with no evidence of serious safety concerns. Becuase⁣ cancers caused by HPV can take many years to develop, ⁤most studies did not follow participants⁢ for a long enough period to ⁤measure⁤ their direct ‌effects on cancer⁢ itself. However, the vaccines reduced precancerous changes in the cervix and other tissues in people aged 15 to 25, as well as the risk of anogenital warts.
Short-term side effects such as mild pain or swelling at ⁣the​ injection site were common, while ⁢serious side effects were ⁢rare and occurred at similar rates in both the ‌vaccinated⁢ and control ‌(i.e., unvaccinated) groups.

Vaccinare maschi e femmine⁤ prima del rapporto sessuale

The second Cochrane review analyzed evidence from 225 studies involving over 132 million people ⁣ in various countries. The results show that HPV vaccination clearly reduces the​ risk of developing⁤ cervical cancer, precancerous​ changes ⁣in ‍the cervix (known as CIN2+ and CIN3+), and anogenital warts. The‌ results come from studies of various types and with different follow-up periods. In particular, girls​ vaccinated by age 16 were 80% less likely to develop cervical cancer compared to‍ unvaccinated girls. And the danger appears​ lower (even for precancerous alterations

A rise in cases of oral cancers (oropharynx, tonsils,⁢ base of ‌the tongue) is largely attributable to Papillomavirus infection. Pain in the tongue or ulcers that​ do not heal, red or white spots in the mouth, sore throat, persistent hoarseness, pain or‌ difficulty swallowing, swollen neck, or nasal congestion on one side‍ or nosebleeds: ⁤these are the symptoms not to be overlooked ⁣ (if they persist for more than ‍three weeks) to arrive at a diagnosis quickly. Actually, when the⁤ disease is detected early, the chances of recovery are high, but too many patients discover the disease late.

What is the Italian “Sportello Cancro”?

The Italian “Sportello Cancro” (Cancer Information Desk) is a nationwide network‍ of local offices providing free, comprehensive information and support to ⁢cancer patients and their families throughout Italy.

origins ⁢and Purpose

Established in 1986 by the Lega Italiana per ‍la Lotta contro i Tumori (LILT ‍- Italian League for the ⁢Fight Against ‌Cancer),‍ the Sportello Cancro initiative addresses a critical need for accessible and reliable ⁣cancer information. LILT identified a significant gap in support services for individuals ⁤navigating a cancer diagnosis and treatment. The desks aim⁤ to⁣ empower patients by⁣ providing ​them with the knowledge to​ make informed decisions about their care and to⁣ navigate the Italian healthcare system.

Services Offered

The​ Sportello Cancro​ offers a⁢ wide‍ range of services, including:

  • Information on cancer types: Detailed explanations of ⁤different cancers, their⁢ causes, symptoms, ⁤and treatment options.
  • Guidance on rights and benefits: Assistance understanding patient rights within the Italian⁢ National Health Service (Servizio Sanitario nazionale – ‍SSN) ⁤and available financial assistance‍ programs.
  • Psychological‍ support: Access to ‌trained volunteers and professionals offering emotional support and counseling.
  • Practical advice: Help with navigating bureaucratic ‍procedures, accessing specialized care, and finding support groups.
  • Prevention information: Education ⁤on cancer prevention⁢ strategies and early detection methods.

National Network and Accessibility

As of December 31, 2025, LILT operates ‌over ⁢90 Sportello Cancro‍ offices ⁣across ⁣Italy, located ⁤in hospitals, community centers, and LILT regional branches. The official LILT website provides ‍a ⁤directory of all locations and⁢ contact information.Services ‍are typically offered in person, by⁣ phone, and increasingly, through online platforms.

Funding ​and‍ Operation

The Sportello Cancro‌ network is primarily ‌funded by ‌LILT through donations,⁣ fundraising events,⁣ and partnerships with pharmaceutical companies and other organizations. The ‍desks are staffed⁣ by a ​combination of ‍trained ⁢volunteers, healthcare professionals,‍ and LILT ‍employees. LILT reported a total revenue of⁤ €14.8 million in 2023,with a ⁢significant portion allocated to the Sportello Cancro network and other patient ⁢support⁤ programs. (LILT⁣ 2023 Transparency Report)

The Sportello Cancro represents a vital resource for cancer patients and their families in Italy, providing crucial information, support, and ⁢advocacy during a challenging time.

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