Human Papillomavirus (HPV) Vaccine Recommendations
Table of Contents
The HPV vaccine is routinely recommended for adolescents,ideally starting at ages 11 or 12,but can be administered as early as age 9. Vaccination is also recommended for individuals through age 26 who were not previously vaccinated.
The Centers for Disease Control and Prevention (CDC) recommends the HPV vaccine because it prevents infection with HPV types that can cause several cancers and genital warts.
As of January 22, 2026, the recommendations remain consistent with those published by the CDC. CDC HPV Vaccination Data
Vaccination Schedule and Age Limits
The HPV vaccine is most effective when administered before any exposure to HPV.
The recommended schedule is a two-dose series for those who begin vaccination before their 15th birthday, spaced 6-12 months apart. for those who start vaccination at age 15 or older, a three-dose series is recommended, administered over a 6-month period. CDC HPV Vaccination Schedule
While not routinely recommended for adults older than 26, the CDC states that some adults aged 27 through 45 years may decide to get the HPV vaccine after speaking with their doctor if they were not adequately vaccinated when younger. This decision should be based on individual risk factors. CDC HPV Vaccination for adults
Rationale for Vaccination in Males
The HPV vaccine is recommended for males as well as females because it protects against HPV types that cause cancers affecting males, including cancers of the mouth, throat, penis, and anus, as well as genital warts.
According to the National Cancer Institute, HPV is responsible for an estimated 39,000 cancers each year in the United States. National Cancer Institute – HPV and Cancer
In 2023,approximately 12,600 cases of HPV-associated cancers occurred in women and 26,900 in men. CDC – HPV-Associated Cancers
Effectiveness and Limitations
The HPV vaccine is highly effective in preventing infection with the HPV types it targets.
The vaccine does not treat existing HPV infections or diseases caused by HPV. It is a preventative measure, and its effectiveness is greatest when administered before exposure to the virus. A study published in the *New England journal of Medicine* in 2020 demonstrated a meaningful reduction in HPV-related precancerous cervical lesions following widespread HPV vaccination programs. New England Journal of Medicine – Impact of HPV Vaccination
The 9-valent HPV vaccine protects against nine HPV types, covering approximately 90% of HPV-related cancers. FDA - HPV Vaccines
