Cancer Uses Healthy Cells: A Surprising Trick
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- Cancer cells provide healthy neighboring cells with additional cell powerhouses (mitochondria) to put them to work, researchers report. This surprising discovery sheds light on a novel mechanism by...
- Tumors have developed many strategies and tricks to gain advantages in the body.
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Cancer Cells ‘Hijack’ Healthy Cells for Energy Boost,Accelerating Tumor Growth
Cancer cells provide healthy neighboring cells with additional cell powerhouses (mitochondria) to put them to work, researchers report. This surprising discovery sheds light on a novel mechanism by which tumors manipulate their habitat to promote growth and aggression.
Tumors have developed many strategies and tricks to gain advantages in the body. Led by cell biology professor Sabine Werner at ETH Zurich, researchers have now discovered another surprising trick that certain tumors resort to in ensuring their survival and growth.
In a new study published in the journal Nature Cancer, the biologists show that skin cancer cells are able to transfer their mitochondria to healthy connective tissue cells (fibroblasts) in their immediate vicinity.Mitochondria are the cell compartments that provide energy in the form of the molecule ATP.
The cancer cells use tiny tubes made of cell membrane material to transfer the mitochondria and connect the two cells-much like in a pneumatic tube system. This process, known as mitochondrial transfer via tunneling nanotubes (TNTs), is a key finding of the study.
