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CogLinks Model: Brain Adapts to Changing Rules

October 19, 2025 Jennifer Chen Health
News Context
At a glance
  • This article discusses a new ⁢computer model ⁣called CogLinks that⁢ aims to better understand how the brain makes decisions, ⁣especially under uncertainty, and how disruptions in this process...
  • * the Brain & Uncertainty: The ‍brain constantly makes decisions with incomplete information, relying ⁤on a balance between "optimistic"⁤ and "pessimistic"⁤ neuronal signals.
  • In essence, CogLinks is a powerful tool that bridges⁣ the gap between single-neuron studies and human brain imaging, offering a more nuanced understanding of how the brain learns...
Original source: news-medical.net

Summary ‍of the Article: Brain Decision-Making ⁤and the CogLinks Model

This article discusses a new ⁢computer model ⁣called CogLinks that⁢ aims to better understand how the brain makes decisions, ⁣especially under uncertainty, and how disruptions in this process ‍can contribute to psychiatric disorders.

Key takeaways:

* the Brain & Uncertainty: The ‍brain constantly makes decisions with incomplete information, relying ⁤on a balance between “optimistic”⁤ and “pessimistic”⁤ neuronal signals. Imbalances ⁤can lead to misinterpretations of the world, ‍seen in conditions like schizophrenia and OCD.
*‍ The⁢ Challenge of studying brain Activity: Customary fMRI technology tracks blood flow, not the direct electrical activity of neurons, making it difficult to understand the underlying mechanisms of decision-making.
* CogLinks – A‍ biologically Realistic⁤ Model: CogLinks is a new ⁣model that simulates brain circuits with a high degree of biological accuracy,mirroring real neuron connections and how ⁣they ⁣process ambiguous information.⁣ It’s designed to be clear, showing how decisions are made, unlike “black box” AI systems.
* ‍ Research Findings: Using CogLinks,⁣ researchers found ⁤that weakening‍ the connection ⁤between ⁣the prefrontal cortex ⁢and the ‍mediodorsal thalamus led to slower, ⁣habit-driven learning.
* Human Confirmation via fMRI: A companion fMRI study with human volunteers playing a game with ⁣changing⁤ rules confirmed the model’s ⁢prediction: the mediodorsal thalamus is crucial for recognizing rule changes and switching between flexible and habitual learning.
* Implications: This research provides insights into the neural ⁢pathways involved in adaptability and could help understand and possibly treat psychiatric disorders linked to impaired decision-making.

In essence, CogLinks is a powerful tool that bridges⁣ the gap between single-neuron studies and human brain imaging, offering a more nuanced understanding of how the brain learns and adapts to a changing world.

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Related

brain, Cortex, Hyperactivity, Imaging, Medicine, Neurons, Neuroscience, psychiatry, Research, schizophrenia, Thalamus

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