Control Blood Pressure to Reduce Alzheimer’s Risk
- Aggressive blood pressure management could significantly decrease the likelihood of developing dementia, according to a recent study published in Nature Medicine.
- The German Heart Foundation recommends an optimal blood pressure target of 120/80 mmHg for overall cardiovascular health.
- Researchers in the United States theorize that adopting a healthy lifestyle can mitigate both hypertension and the risk of dementia.
Lowering Blood Pressure May Reduce Dementia Risk, Study Finds
May 2, 2025
Aggressive blood pressure management could significantly decrease the likelihood of developing dementia, according to a recent study published in Nature Medicine. The research highlights the potential benefits of comprehensive therapy approaches in maintaining cognitive health.
The German Heart Foundation recommends an optimal blood pressure target of 120/80 mmHg for overall cardiovascular health. Now, emerging evidence suggests that maintaining blood pressure within this range may also offer significant protection against cognitive decline.
Researchers in the United States theorize that adopting a healthy lifestyle can mitigate both hypertension and the risk of dementia. Separate research indicates that shingles vaccination might also provide a protective effect against dementia.
Study Highlights Importance of Blood Pressure Control for Dementia Prevention

A team at the University of Texas Southwestern Medical Center investigated the correlation between blood pressure and dementia risk. The study involved analyzing data from 33,995 participants residing in rural China, all aged 40 or older and without prior treatment for hypertension.
Participants were divided into two groups. One group received intensive blood pressure therapy,encompassing medication,lifestyle counseling (including weight management and reduced salt and alcohol intake),and at-home blood pressure monitoring. The second group received standard care, involving routine blood pressure checks and general lifestyle recommendations.
After a four-year period, the study revealed that the group receiving intensive blood pressure control experienced a 15% reduction in dementia risk compared to the control group. Furthermore, this group also demonstrated a 16% decrease in the risk of cognitive impairment. These findings underscore the importance of proactive blood pressure management in dementia prevention.
Expert Commentary
Jiang He, a lead author of the study, advocates for the global implementation of similar interventions to mitigate the effects of dementia. tara Spires-Jones, a professor at the University of Edinburgh, told New Scientist magazine that while managing high blood pressure doesn’t guarantee dementia prevention, it is a crucial factor, alongside addressing other risk factors like smoking, inactivity, and social isolation.
