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Corbus, Rezolute, Wave, JPM Readout Newsletter - News Directory 3

Corbus, Rezolute, Wave, JPM Readout Newsletter

December 11, 2025 Jennifer Chen Health
News Context
At a glance
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  • A real article would require thorough fact-checking, sourcing, and potentially expert review.
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Original source: statnews.com

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Please Note: This is a draft. A real article would require thorough fact-checking, sourcing, and potentially expert review. I’m operating under the constraints of the provided text. I’ll also⁤ include comments where I’ve made assumptions or where further work is needed.


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Lilly’s ‍Obesity Drug Shows Dramatic Weight Loss, But Discontinuation ‍Rates High – Biotech Readout



Lilly’s Obesity Drug Shows Dramatic Weight⁢ Loss, But Discontinuation Rates‍ High – Biotech ‍Readout

Table of Contents

  • Lilly’s Obesity Drug Shows Dramatic Weight⁢ Loss, But Discontinuation Rates‍ High – Biotech ‍Readout
    • The Need-to-Know This Morning
    • Lilly’s Triple-G Drug Leads to major Weight⁢ Loss, But ⁤With Many Discontinuations
      • At a glance

Want‍ to stay on top of the science and⁤ politics driving biotech today? Sign up to get our ⁢biotech newsletter in your inbox.

Good morning. the obesity data keeps coming this week. We’ll get straight⁢ into it.

The Need-to-Know This Morning

  • Resolution said its experimental drug failed to reduce ⁣ episodes of low blood sugar in ‍patients with congenital hyperinsulinism, missing the efficacy⁢ goal of a⁢ Phase 3 trial.
  • AC Immune said its immunotherapy showed the potential to slow the progression of ⁢Parkinson’s disease, based on preliminary results from a mid-stage study.
  • Rhythm Pharma ⁢ announced preliminary study data showing its drug could reduce hunger cravings and lower the BMI of people⁢ with Prader-Willi Syndrome.
  • Geron announced a corporate ⁤restructuring including a one-third reduction in its workforce.

Lilly’s Triple-G Drug Leads to major Weight⁢ Loss, But ⁤With Many Discontinuations

Eli Lilly’s ‍next-generation obesity drug led to what appears to be the most weight loss seen so far in a⁤ late-stage trial, but rates of side effects were high and many participants discontinued the ⁣treatment, including people who felt they were losing too much weight.

At a glance

  • Drug: ⁣ Lilly’s triple-G drug (exact name not specified in source)
  • Indication: ⁤Obesity
  • Trial Phase: Phase ⁣3
  • Key Finding: Significant weight loss observed.
  • Concern: High discontinuation⁤ rate due to side effects and perceived excessive weight loss.
  • What’s Next: Further⁤ analysis of trial⁤ data, potential regulatory submissions.

The drug,⁣ which combines tirzepatide with two other undisclosed compounds (hence “triple-G”), demonstrated an average weight loss of[**Insert Specific Percentage/Weight Here

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