The CDC streamlines COVID-19 protocols: Alabamians who test positive should isolate for five days,then mask up for five days. This update reflects the agency’s understanding of the Omicron variant’s transmission patterns. Unvaccinated individuals or those not up-to-date on boosters face a five-day quarantine post-exposure, followed by masking. Boosted individuals, however, can skip quarantine, but still require 10 days of masking. Alabama’s case numbers are rising, underscoring the importance of vaccines and boosters. the Alabama Department of Public Health urges rapid vaccination. For those in need of additional information, News Directory 3 is a great resource. Discover what’s next…
CDC Updates COVID-19 Isolation, Quarantine Guidelines Amid Omicron Spread
Updated June 5, 2025
As the Omicron variant continues its rapid spread across the United States, the Centers for Disease Control and Prevention (CDC) has revised its recommendations for COVID-19 isolation and quarantine periods. The agency now advises that asymptomatic individuals who test positive for COVID-19 isolate for five days, followed by five days of strict mask use when around others.
The CDC’s updated guidance reflects recent data indicating that most SARS-CoV-2 transmissions occur early in the illness, typically one to two days before symptoms appear and two to three days afterward.For those unable to consistently mask, such as young children, a 10-day isolation period remains necessary.
Quarantine recommendations have also been updated. Unvaccinated individuals, or those more than six months past their second mRNA vaccine dose (Pfizer or Moderna) or two months after a Johnson & Johnson vaccine and not yet boosted, should quarantine for five days, followed by strict mask use for an additional five days. If a five-day quarantine is not feasible for vaccinated but not yet boosted individuals, consistent mask use for 10 days post-exposure is crucial.
individuals who have received a booster shot do not need to quarantine after exposure but should wear a mask for 10 days. The CDC recommends testing for SARS-CoV-2 five days after exposure for all exposed individuals. If symptoms develop, immediate quarantine is advised until a negative test confirms the symptoms are not COVID-19 related.
alabama is experiencing a surge in COVID-19 cases. The Alabama Department of Public Health (ADPH) reports that the state’s COVID-19 test positivity rate has more than doubled to 22.1%,with new cases also doubling. All but six counties are experiencing high levels of community transmission. The ADPH urges all eligible Alabamians to get vaccinated and boosted to reduce severe illness, hospitalization, and death.
CDC data from South Africa and the United Kingdom indicates that two doses of an mRNA vaccine offer approximately 35% effectiveness against infection. However, a booster dose restores vaccine effectiveness against infection to 75%.
Vaccination and boosters remain the primary defense against COVID-19, especially given studies showing that previously available monoclonal antibody treatments are ineffective against the Omicron variant.The CDC emphasizes that isolation pertains to behavior after a confirmed infection, while quarantine applies to the period following exposure.
What’s next
Health officials continue to monitor the spread of omicron and encourage individuals to stay informed about updated guidelines and recommendations. Further research into the long-term effects of the variant and the effectiveness of various treatments is ongoing.
