Delirium Reduction: Music Therapy for Older Adults
- Delirium, a state of acute confusion, is a notable concern for critically ill patients, especially those over the age of 50.
- The Decreasing Delirium thru Music in Critically Ill Older Adults (DDM) Trial was a multi-center, randomized, controlled trial designed to assess the efficacy of slow-tempo music in reducing...
- The trial enrolled critically ill adults aged 50 years and older admitted to ICUs.
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Music Therapy Shows Limited Impact on Delirium in Critically Ill Older Adults
Table of Contents
Understanding Delirium in the ICU
Delirium, a state of acute confusion, is a notable concern for critically ill patients, especially those over the age of 50. Approximately 75% of older adults experience delirium during their stay in the Intensive Care Unit (ICU). This isn’t merely a temporary state of disorientation; delirium carries serious short- and long-term health consequences, including an increased risk of post-ICU dementia, prolonged hospital stays, and higher mortality rates.
The DDM Trial: Study Design and Methodology
The Decreasing Delirium thru Music in Critically Ill Older Adults (DDM) Trial was a multi-center, randomized, controlled trial designed to assess the efficacy of slow-tempo music in reducing delirium and related symptoms. The study was conducted at Indiana University School of Medicine-affiliated hospitals and Mayo Clinic, involving a collaborative team of researchers from multiple institutions including IU School of Medicine, Mayo Clinic, Regenstrief Institute, Anglia Ruskin University and Area 10 Labs.
The trial enrolled critically ill adults aged 50 years and older admitted to ICUs. Participants were randomly assigned to one of two groups:
- Music Group: Received twice-daily sessions of carefully curated slow-tempo music (60-80 beats per minute) for up to seven days.
- Control Group: Received a silence-track control, also delivered twice daily for up to seven days.
Both groups listened to their assigned audio through computer tablets and over-the-ear active noise-cancelling headphones. The study employed concealed outcome assessments to minimize bias. A key achievement of the DDM Trial was demonstrating the feasibility of centralized, app-based music playlist delivery within the demanding ICU surroundings.
Key Findings: What the study Revealed
The results of the DDM Trial, published in the Journal of the American Medical Association’s JAMA Internal Medicine, indicated that twice-daily slow-tempo music did not significantly shorten the duration of delirium or coma, nor did it reduce delirium severity, pain, or anxiety compared to the silence-track control.
However, the study did reveal some engaging trends:
- Patients who received at least seven doses of slow-tempo music showed a trend toward fewer days with delirium/coma.
- There was also a trend toward fewer days of delirium/coma among patients who had been administered benzodiazepines (sedatives known to increase delirium risk).
These trends suggest that music may have a subtle beneficial effect, particularly when combined with careful management of sedative medications. Though, the findings are not conclusive and warrant further examination.
Data Summary
| Outcome Measure | Music Group | Control Group | P-value |
|---|---|---|---|
| Delirium/Coma Duration (days) |
|