Diabetes Medication Reduces Alcohol Use: Promising New Hope for Recovery

New research from the University of Nottingham shows that some diabetes medications may help reduce alcohol use. This study focused on GLP-1 receptor agonists (GLP-1 RAs), a type of diabetes treatment.

Dr. Mohsen Subhani led the study, which appears in the journal eClinicalMedicine. The research was funded by the National Institute for Health and Care Research (NIHR).

Researchers reviewed existing studies on GLP-1 RAs and their effects on alcohol consumption. Their key findings include:

• In one study, the drug exenatide did not significantly reduce drinking overall after six months, but individuals with obesity experienced some positive effects.
• Another study found that users of dulaglutide were 29% more likely to cut down on drinking compared to those taking a placebo.
• Observational studies indicated that people on GLP-1 RAs had fewer alcohol-related health issues and lower overall alcohol use than those on other treatments.

Dr. Subhani noted that GLP-1 medications may target the brain’s reward center, particularly benefiting individuals with a BMI over 30.

For further details, the study is available in eClinicalMedicine with the reference: Subhani, M., et al. (2024). Association between glucagon-like peptide-1 receptor agonists use and change in alcohol consumption: a systematic review. DOI: 10.1016/j.eclinm.2024.102920.