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Insights into mRNA vaccines and building a protective shield against mutant COVID-19.

An in-depth look at mRNA vaccines and building a protective shield against mutant COVID-19 by Prof. Dr. Nithi Mahanon, secretary-general of the Royal College of Chulabhorn. A comparative study of immune levels after Moderna mRNA vaccination as a booster needle. by Chulabhorn Royal College Advice on vaccination with a booster needle from an expert.

will overcome covid-19 The booster vaccine must come

Just a few weeks after COVID-19 was discovered. The omicron strain was first introduced in the world during November 2021. This new strain of worrying COVID-19 has spread to more than 90 countries around the world. Data from Modena and Pfizer just before Christmas revealed that the third dose of the COVID-19 vaccine, or booster Help the immune system come back up. This helps prevent infection and reduce severe symptoms. Thai people have also begun to question whether We must vaccinate against COVID-19. Silk booster needle, how many injections and quantity of booster vaccine for Thai people how much is appropriate

Prof. Dr. Nithi Mahanon, secretary-general of the Chulabhorn Royal College, confirmed that the COVID-19 vaccination Stimulation needles are very necessary. because of covid-19 New species are emerging all the time. And it’s natural that the germ wants to survive. Therefore, we adapt to escape the immune system in our body continuously. There are 2 ways to manage the virus from escaping us, which is to increase our immunity or find a new vaccine. But for COVID-19 with this continuous epidemic Finding a new vaccine is difficult because it takes time.

“Stimulating the immune system down is the solution right now. The same thing is with vaccines or generic drugs, once the body has received the vaccine or drug. Immunity stays high for a while before gradually decreasing. Therefore, we must constantly be encouraged. to maintain high immunity until we have a new COVID-19 vaccine or COVID-19 is no longer an epidemic. and became like a seasonal flu.”


The key question now is the quantity of the COVID-19 vaccine. How much stimulation needles are needed to be appropriate? The Chulabhorn Royal College is now conducting a comparative study on immunity levels after 50 micrograms and 100 micrograms of moderna mRNA vaccination with the mRNA vaccine, and will focus on research among those who have received the vaccine. -19 Both the first doses of vaccine are of the same type, e.g. the first 2 doses of Sinofarm vaccine or the first 2 doses of Astrazeneca vaccine.

Why this research is needed in Thailand Because studying abroad Most of the population received the first and second dose of mRNA vaccination. In Thailand, in the first phase, most people received the inactivated vaccine. Before it was a viral vector vaccine. The results of foreign studies may therefore have different information. Therefore, it is necessary to conduct a research study specifically for Thailand.

The study will focus on the degree of immunity to the spike protein that the virus binds to the body’s cellular receptor, IgG, and use the mRNA vaccine as a booster as global research confirms that mRNA vaccines are. Vaccines that stimulate immunity better than other vaccines

“Right now we don’t have a vaccine that protects against a specific strain. Therefore, we have to rely mainly on the mRNA vaccine that stimulates the immune system and it takes 2-3 months to complete. Therefore, the research results should be known around February 2022,” said Prof. Dr. Nithi.

In the meantime, Prof. Dr. Nithi recommends that People should understand about the prevention and treatment of COVID-19. including keeping track of academic information Because new information is constantly coming out. At the same time, pharmaceutical companies are constantly developing new vaccines.

“We shouldn’t be overly concerned with ever-changing information. Because doctors have to find the best way for people. What everyone should do is that we must learn to live with this disease. Try to stay in a well-ventilated place. wear a mask to wash your hands not too close to each other But humans are social animals. It can’t be that far apart, so vaccines are very important at the moment. and should receive a booster vaccine to keep the immune system from dropping too much,” said Prof. Dr. Nithi.

For those who have received the mRNA vaccine, Prof. Dr. Nithi recommends leaving about 4-6 months before receiving the booster vaccine. For those who have received the inactivated vaccine Should leave about 2-3 months and viral vector 3-6 months, however, the distance before the injection of the stimulant may change. depending on the rate of outbreaks in society risk of infection Including the risk of congenital disease of each person that will increase the severity of the disease.

The booster dose of the COVID-19 vaccine is therefore the most effective option. Until the World Health Organization announces that the COVID-19 outbreak has ended.

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