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Lundquist Institute Researcher Receives NIH Funding for ICU Care

October 27, 2025 Dr. Jennifer Chen Health

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Dr. chang Receives NIH Funding to Expand Time-Limited Trial Model ⁣in ICU Care

Table of Contents

  • Dr. chang Receives NIH Funding to Expand Time-Limited Trial Model ⁣in ICU Care
    • Improving Communication and Reducing Needless Treatments ⁢in‌ Intensive Care
    • Large-Scale Trial Across​ Two Major⁢ Healthcare Systems
    • Impact ⁤and Future implications
      • At a Glance

Published October 27, 2023, ⁣20:56:54 PST

Improving Communication and Reducing Needless Treatments ⁢in‌ Intensive Care

Dr. David Chang,along ⁢wiht his research⁢ team,has been awarded ⁢a substantial grant from the National Institutes of Health (NIH) to conduct a large-scale clinical trial of a⁢ novel communication strategy in intensive care units (ICUs). This strategy⁣ centers around​ “time-limited‍ trials” (TLTs)⁢ of treatments and shared decision-making between care teams, patients,‍ and their families.

Recognizing existing gaps ⁣in⁣ communication within ICU settings, Dr.‌ chang’s team developed a structured approach. ‍ TLTs involve agreeing on treatment goals, establishing ‍defined timeframes for interventions, and regularly ⁤reassessing outcomes collaboratively. initial pilot studies demonstrated that TLTs‍ not only improved the⁤ quality of communication⁢ but also led to ‌a reduction in the​ use of treatments deemed non-beneficial to patients. The Lundquist Institute originally reported⁣ on these promising results.

Large-Scale Trial Across​ Two Major⁢ Healthcare Systems

The newly awarded NIH R01 funding will enable Dr. Chang’s team to implement and evaluate the TLT model across two diverse‌ healthcare systems in ‌Southern California:

  • los⁤ angeles County Department ‌of ‍Health Services​ (LAC DHS): The second-largest public healthcare system in the United​ States, serving a broad and diverse patient population. Learn⁣ more about LAC DHS.
  • Kaiser Permanente southern california (KPSC): The region’s largest integrated healthcare ‌system, known for its coordinated care model. Learn ⁣more about KPSC.

The selection‌ of ​these two systems‍ is deliberate. Their differing structures and the diverse⁢ cultural and socioeconomic backgrounds of their patient populations will​ allow researchers to⁣ assess the adaptability and effectiveness of the TLT model in a variety of real-world settings.

Impact ⁤and Future implications

The Lundquist Institute ⁣highlights that this research⁤ has the potential to transform ICU care nationwide by fostering greater shared decision-making between medical professionals,patients,and⁤ their families.By combining scientific innovation with a compassionate approach, Dr.Chang’s work aims to improve patient outcomes and ensure that treatment aligns ​with individual values and goals.

At a Glance

  • What: A large-scale clinical trial ⁤of a time-limited⁤ trial (TLT) model for ICU treatment decisions.
  • Who: led by dr. David Chang​ and his team at The Lundquist Institute.
  • Where: los angeles County Department of Health Services (LAC DHS) and Kaiser Permanente Southern California ‍(KPSC).
  • Why it⁢ Matters: Potential to improve communication,⁢ reduce unnecessary treatments, ​and enhance shared ​decision-making in ICU⁤ care.
  • What’s Next: ⁢Implementation and evaluation of the TLT model ⁣across the two healthcare systems.

– drjenniferchen

The emphasis on time-limited ⁢trials‌ is​ a significant ‌shift in ICU practice. Historically, ‍treatment decisions have often been protracted, leading to prolonged suffering for patients and emotional distress for‌ families. The TLT model introduces ⁢a structured framework for evaluating treatment‍ effectiveness within a defined timeframe, promoting more focused and realistic conversations about goals⁤ of care. ‌The‌ choice of LAC DHS ‌and KPSC is also strategically important; studying⁤ implementation ⁤within ⁣both​ a public and integrated healthcare system

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