Mahidol University collaborates with the Department of Health to train “family doctors” focusing on genomic testing to raise public awareness. Change your lifestyle to maintain good health. Delay aging in line with the context that Thailand is moving towards an aging society. Ready to continue with genomic technology Towards sustainable health
Genomic medicine technology in the post-COVID-19 era has undergone tremendous changes. Previously, the emphasis was on deciphering the entire genome of emerging pathogenic viruses, such as SAR-CoV-2, in order to track the spread of subspecies. Develop vaccines and antiviral drugs to decode genetics The entire genome of patients who were not vulnerable but had severe symptoms A Covid situation occurred. or died To investigate the genes that may be involved as a cause. which will lead to prevention and precision treatment
Medicinal)
Now we have entered the era. “Epigenetics” (Epigenetics) It aims to study the expression of genes that are controlled by the addition of certain chemicals to DNA strands at certain positions due to environmental influences. without altering the genetic code sequence. This process influences the biological or epigenetic clock linked to the development of chronic non-communicable diseases (NCDs).
Professor Emeritus Dr. Wasan Chandrathit, Director of the Medical Genome Center Faculty of Medicine Ramathibodi Hospital Mahidol University It describes a medical service currently observed around the world: the genetic decoding of the entire genome of both patients and healthy people. Including microorganisms and viruses in the human body that affect health conditions. Especially in the field of anti-aging medicine. which uses the detection of chemical changes on the DNA strand Also known as “Epigenetics” which will help the world’s population have access to more precise and targeted healthcare and treatment.
These innovations have expanded the reach of healthcare. It is not limited to the role of the attending physician alone. but also encourage everyone to have a deep understanding of health (Health Literacy) and to participate in changing their lifestyles for sustainable good health (wellbeing) in order to delay aging. To be in line with the context of Thailand where an aging society has fully intervened.
Today, the leading cause of death for humanity worldwide is no longer due to infectious diseases as in the past. Even though there have been as many as 775 million people infected with COVID-19 in the last 4 years, there are only 7 million of them. people died, or 0.9%, as a result of scientific advances in decoding SARS-CoV-2 mutations (SARS-CoV-2 genomic surveillance) to monitor epidemics. Develop vaccines and antiviral drugs
“Chronic non-communicable diseases” (NCDs) have a high mortality rate of approximately 41 million people worldwide every year.
What is worrying, however, is the death toll from “Non-communicable diseases” (NCDs) which have a high mortality rate of around 41 million people every year worldwide, or around 71-74% of all deaths every year . Be it diabetes Stroke, heart disease, emphysema, high blood pressure. High blood fat, abdominal obesity, cancer and many more.
Prevention and drug treatment can reduce the risk of these non-communicable diseases by only 20-30%, but healthy lifestyle changes such as controlling weight, blood pressure, fat, sugar, stress and of regular physical exercise. Quit smoking and addictive drugs Stop drinking alcohol Get enough sleep Have good relationships with the people around you It can help reduce the risk of heart disease and stroke by up to 70 – 90% and also extend the life expectancy of 24 years in men and 21 years in women. For this reason, nowadays, health-conscious people around the world are turning to it. The importance of seriously changing the way you live (Lifestyle)
The training of “Family Doctors” focuses on genetic tests to raise public awareness.
In this issue, the Medical Genome Center Faculty of Medicine Ramathibodi Hospital Mahidol University collaborated with the Department of Health, Ministry of Public Health to train medical residents in the field of preventive medicine. (lifestyle medicine) with a focus on genomic testing to raise awareness and spark inspiration for lifestyle changes, such as tailoring diet and exercise based on genes. (Nutrigenomics and exercise genomics)
Furthermore, there is the problem of children’s adaptation to germs in the environment. that they had never faced before Because they had to live at home during the COVID-19 crisis without having the opportunity to interact with other children. Until it causes an immune gap (Immunity Gap) which leads to the recurrence of the disease. and emerging diseases in children after the World Health Organization COVID-19 public health emergency has been lifted.
For this reason the Medical Genome Center Faculty of Medicine Ramathibodi Hospital Mahidol University Therefore, has come to play a role in decoding genetics from children’s samples. To look for types of microorganisms or viruses that children are infected with as well as checking whether or not there is a vaccine against such germs or those bacteria are resistant to antimicrobial drugs. Or which virus? It uses clinical metagenomics sequencing technology, which can decode the genetics of both DNA and RNA of microorganisms. and viruses directly from the sample. It is not necessary to cultivate them to increase their numbers in the laboratory. This is to use the information obtained for prevention. and treat infectious diseases in children more carefully
Another important thing is to check the quantity and type of microorganisms present in the body (Microbiome) that influence our state of health.
Decoding modern genetics (Next Generation Sequencing)
With the advancement of modern genetic decoding technology (Next Generation Sequencing), the scope of research in the field of genomics is not limited to the analysis of DNA only in human cells. But we can also analyze the effects of the microorganisms that live in us. This leads to designing ways to address and “deal with the disease” that is expected to occur in the future. and can also be applied to expand findings to the community more broadly.
This was added by Professor Emeritus Dr. Wasan Chandrathit The provision of genetic testing services in Thailand is considered to be at the “leading” level in ASEAN, as can be seen from more than 500 laboratories nationwide that have been certified by the Ministry of Public Health to be able to screen for COVID-19 using real-time PCR technique, which laboratory personnel These have the potential to develop skills (Reskill) or upgrade skills (Upskill) to efficiently provide medical genomics and public health services.
In this regard, Mahidol University of Medical Genome Center Faculty of Medicine Ramathibodi Hospital ready to do the duty “The wisdom of the earth” according to the aspiration of Mahidol University Provide genomic analysis services to people from birth to old age.
This can be seen from the Thai whole genome deciphering work (Low Coverage Whole Genome Sequencing) through the provision of maternal blood infant DNA testing (NIPT) services to screen for chromosomal abnormalities. There are more than 30,000 cases, including genetic decoding. The entire genomes of over 1,000 healthy people were analyzed using Next Generation Sequencing (NGS) technology, both short read and long read, in order to represent a major force for the nation in reducing of disease rates and lead to sustainable health in both the current generation and generations to come
#Mahidol #University #partners #Department #Health #train #family #physicians #continue #advance #genomic #technology #sustainable #health
