Breast cancer is widely recognized as a health concern primarily affecting women, but it’s a disease that can, and does, impact men as well. While rare, male breast cancer is increasingly being recognized as a distinct clinical entity, and recent data from Nayarit, Mexico, highlights the importance of awareness and early detection in the male population.
At the end of 2024, health officials in Nayarit reported 73 cases of breast cancer, two of which were in men. By 2025, that number had risen to 158 total cases, including one male diagnosis. As of epidemiological week 4 of to , nine new cases were detected in Nayarit, with one again being a male patient. This brings the total number of cases detected in the state so far this year to 10, confirming that while infrequent, male breast cancer is a reality.
The underlying cause of breast cancer in both men and women involves uncontrolled growth of cells within breast tissue. Although men have significantly less breast tissue than women, they still possess a small amount, making them susceptible to developing the disease. According to specialists at the Mayo Clinic, this uncontrolled growth occurs when cells accumulate alterations in their DNA, leading to rapid multiplication and the potential formation of tumors that can invade other organs.
The most common type of breast cancer seen in men is ductal carcinoma, originating in the milk ducts. Less frequent types include lobular carcinoma (originating in the lobules), Paget’s disease (affecting the skin of the nipple and areola), and inflammatory cancer. A study published in analyzing male breast cancer cases in Mexico found a significantly high proportion of patients presented with advanced disease and a triple-negative subtype, indicating a more aggressive form of the cancer.
Several factors can increase a man’s risk of developing breast cancer. These include increasing age – with most cases occurring after age 60 – a family history of breast cancer (in either men or women), and genetic mutations, particularly in the BRCA1 and BRCA2 genes. Klinefelter syndrome, a genetic condition where a male is born with an extra X chromosome, is also a known risk factor. The Mexican study noted a germline BRCA pathogenic variant was identified in 8.33% of the patients analyzed.
One of the biggest challenges in addressing male breast cancer is a lack of awareness. Men may be less likely to consider a lump in their chest as a potential sign of cancer, often attributing it to other causes or simply ignoring it. This delay in seeking medical attention can lead to later-stage diagnoses and more challenging treatment outcomes. Symptoms to watch for include a lump or mass in the chest, changes to the skin of the chest, nipple discharge, or pain or retraction of the nipple.
Treatment for male breast cancer typically involves surgery, often followed by chemotherapy or radiation therapy, depending on the stage and characteristics of the cancer. The Mexican study highlighted a significant proportion of patients exhibiting primary endocrine resistance, meaning the cancer did not respond to hormone therapy, a common treatment approach for some breast cancers. This underscores the need for further research into effective treatment strategies for male breast cancer, including investigation into somatic mutations.
The increasing recognition of male breast cancer cases in Nayarit, and the broader context of underdiagnosis highlighted in a report from , emphasizes the importance of expanding awareness and prevention efforts to include men. While breast cancer remains predominantly a disease affecting women – with approximately 82,000 cases occurring among women compared to 65,000 among men annually, according to data from – the fact that it can affect men at all necessitates a more inclusive approach to public health messaging and screening recommendations. Early detection remains crucial for improving outcomes, and that requires educating men about the signs and symptoms and encouraging them to seek medical attention promptly if they notice any changes.
The cases of individuals like Andrés Torres and José Luis Castillo Preciado, as reported in Mexico, serve as a reminder that male breast cancer is not just a clinical issue, but also a social and economic challenge. Increased visibility, early detection initiatives, and robust support networks are essential to address this often-hidden health concern.
