The Centers for Disease Control and Prevention (CDC) continues to emphasize the importance of vaccination against shingles, a painful condition that can develop in individuals who have previously had chickenpox. Current recommendations, updated as of , focus on the recombinant zoster vaccine (RZV), marketed as Shingrix.
Who Should Get Vaccinated?
The CDC recommends two doses of Shingrix for adults aged 50 years and older to prevent shingles and its complications. This recommendation applies regardless of whether an individual has previously had shingles or received the older, now-discontinued Zostavax vaccine. Screening for prior varicella (chickenpox) infection is also not necessary before administering the vaccine.
Importantly, vaccination is also recommended for individuals 19 years of age and older who are or will be immunodeficient or immunosuppressed due to disease or therapy. This broader recommendation recognizes that those with weakened immune systems are at increased risk of developing shingles.
Understanding Shingles
Shingles, also known as herpes zoster, is a reactivation of the varicella-zoster virus – the same virus that causes chickenpox. After a person recovers from chickenpox, the virus remains dormant in nerve cells. Shingles occurs when this virus is reactivated, causing a painful rash that typically appears on one side of the body. While most cases resolve within a few weeks, some individuals experience long-term nerve pain, known as postherpetic neuralgia, which can persist for months or even years.
The Shingrix Vaccine: What You Need to Know
Shingrix is a non-live, recombinant vaccine. This means it does not contain a weakened version of the virus and cannot cause chickenpox. The vaccine works by stimulating the immune system to produce antibodies against the varicella-zoster virus, providing protection against shingles.
The CDC recommends two doses of Shingrix, administered 2 to 6 months apart. If more than 6 months have elapsed since the first dose, the second dose should be administered as soon as possible without restarting the vaccine series.
Can Shingrix Be Given With Other Vaccines?
Yes. Recombinant and adjuvanted vaccines, like Shingrix, can be administered at the same time as other adult vaccines, but at different anatomical sites. This includes the COVID-19 vaccine. Studies are ongoing to evaluate the coadministration of Shingrix with adjuvanted influenza vaccines (Fluad) and COVID-19 vaccines.
Shingles Vaccine for Those Under 50
While the primary recommendation is for adults 50 and older, the vaccine is also approved for individuals 19 years and older with certain immune conditions that increase their risk of shingles. These conditions may include HIV infection, cancer treatment, or the use of immunosuppressant medications following an organ transplant. It’s crucial for individuals with these conditions to discuss vaccination with their healthcare provider.
Why Vaccination is Important
Shingles can be a debilitating condition, and vaccination is the most effective way to prevent it. Even if shingles does occur in a vaccinated individual, it is generally less severe than in those who are unvaccinated. The CDC’s recommendations reflect the ongoing commitment to protecting public health and reducing the burden of this painful and potentially chronic disease.
As of , updated vaccination guides are available to help individuals ensure they are up-to-date on recommended vaccines, including Shingrix. Healthcare workers who directly interact with patients or handle potentially infectious materials are also encouraged to ensure they are appropriately vaccinated.
Staying Informed
For the most up-to-date information on shingles vaccination, consult with your healthcare provider or visit the CDC website. Vaccination is a safe and effective way to protect yourself from the pain and complications of shingles.
