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Study Shows High Genetic Risk Linked to Increased Cardiovascular Disease Risk for Koreans

Research conducted by the Korea Agency for Disease Control and Prevention… “People at high genetic risk are 5 times more likely to develop cardiovascular disease”
“Tailored disease prediction and prevention possible for Koreans at high risk of cardiovascular disease”

▲Myocardial infarction

It was found that people with a high “clinical risk” calculated by combining age, sex, blood pressure, smoking habits and obesity had a 3.6 times greater risk of developing cardiovascular disease than the low-risk group.

When genetic risk is added, the risk of developing cardiovascular disease increases fivefold.

The Korea Disease Control and Prevention Agency announced on July 9 that it has published the “results of a cardiovascular disease risk prediction study adapted to Koreans” in the international academic journal “Frontiers in Genetics.”

The National Institute for Disease Control and Prevention analyzed clinical data, genetic information, and 17-year follow-up outcomes of 7,612 community cohorts (same group) during the Korea Genome Epidemiology Survey project.

As a result, the high-risk group with a “clinical risk” of 7.5% or more, which calculated the risk of developing cardiovascular disease in the next 10 years using factors such as age, sex, systolic blood pressure, diabetes, cholesterol , and smoking status, has a higher cardiovascular risk than the low-risk group with a risk of less than 7.5%. The risk of developing the disease was 3.6 times higher.

People in the top 20% of people with a high “genetic risk” score, which is a score that combines disease-related genetic factors, had a risk of developing cardiovascular disease that increased about 1.5 times compared to the top 20%. Poorer.

The Korea Disease Control and Prevention Agency explained that even in the low-risk clinical group with a clinical risk of less than 7.5%, the risk of developing cardiovascular disease increased up to 1.5 times with the increased genetic risk.

The risk of developing cardiovascular disease in the high-risk group with both high genetic and clinical risk was five times that of the group with both low.

The Korea Agency for Disease Control and Prevention said: “The American College of Cardiology has developed a tool to predict the onset of cardiovascular disease using clinical information and recommends early prevention through this. The results of this study they are “personalized for Koreans” to predict the high-risk group of cardiovascular disease and prevent the disease. “It can be used as a scientific basis for prevention,” he said.

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[저작권자ⓒ 울산종합일보. 무단전재-재배포 금지]

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