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write a title for this article Because autism is an individual disorder without precise standards, it is difficult to conduct quantitative research and treatment. In a review paper published in Molecular Psychiatry, the development of mouse models of human psychiatric disorders has proven to be a viable method for studying molecular mechanisms, along with a virtual reality system previously developed by the same team, click Introducing the developments latest in current autism research.Effects of Cannabis on Children’s Brain Structure (Gene Online International Edition)Is autism beyond diagnosis and treatment?Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by reduced social communication skills, strong obsession with specific objects, and repetitive behaviors. The number of patients with autism continues to increase and it has become a social problem. As the current diagnosis of autism is still based on behavioral characteristics, a quantitative perspective is lacking, and new biomarkers are urgently needed to aid in diagnosis.Experts continue to debate whether to treat or provide for autism. This reflects that autism has multiple manifestations and causes. It also shows that the diversity of mental disorders is similar to a spectrum So, in the absence of quantitative or objective assessment systems. mechanical diagnostic methods would make it difficult for researchers to analyze the mechanisms of autism and develop potential treatments.Professor Toru Uchi, from Physiology at the Graduate School of Medicine, Kobe University, explained: “Autism is a disease as complex as cancer. Although genetic factors play a more important role in this disease than other mental illnesses, environmental factors are also important .To treat autism, we need to understand the neural networks underlying social adjustment disorders and develop new techniques to manipulate neural networks in humans.”Mouse model mimics brain mechanisms in autismProfessor Uchisho is a pioneer in the development of mouse models of human psychiatric disorders. Genetically modified mice that exhibit social behavior disorders provide a unique opportunity to accurately analyze the molecular and physiological mechanisms at the root of autism, and to testing potential treatments. As an internationally recognized expert in this field, Professor Nai Jiang was invited by the journal Molecular Psychiatry to summarize the current research status.In this paper review, Professor Utsumi emphasized the importance of the insular cortex (Insula) deep in the brain, an area that is interconnected with sensory, emotional, motivational and cognitive systems. In mice, it is involved in the regulation of emotions, empathy, motivation, and many other functions, while in humans it is associated with self-awareness. The review explains in detail which genes and physiological functions of the insular cortex affect the onset of autism. Professor Nai Jiang explained: “Psychiatric illnesses are often considered to be neurocircuitry disorders, and therefore, uncovering neurocircuitry function in social behavior will facilitate the development of neurocircuitry-based treatments in the future. “Mice, Brains, Learned!In recent years, research has been underway to uncover the abnormalities in brain function that characterize autism. Static functional magnetic resonance imaging (fMRI) studies have shown that the density of functional networks in the brains of autistic individuals increases in early childhood and decreases in adulthood. However, such changes vary greatly between individuals, and it is unclear how such abnormalities in active brain networks at rest affect behavior.Autism is closely linked to genetic factors, and genomic abnormalities such as copy number variation (CNV) are associated with brain neuropathology. In recent years, to understand the neuropathology of the brain in autism, animal models that mimic abnormalities in the human genome have been used.Professor Uchigo’s research team recently published in “Cell Report” (Cell Report), saying that the team has developed a virtual reality (virtual reality, VR) system, which can measure a wide range of cortical neural activity when mice are active. Enable researchers to reveal abnormalities in the dynamics of cortical functional networks in autism model mice, which are dense and less modular. Using machine learning, they were also able to distinguish with high accuracy between autism model mice and wild-type mice based on patterns of cortical functional networks when the mice started running or stopped running.Professor Naismith said: “We are very interested in the human mind. By understanding the pathology and physiology of autism, I hope to understand how human thought is produced in the brain. “Through research, Professor Naismith is trying understand the brain of the molecular basis of function, I hope that after a better understanding of the human brain, it can be useful for the diagnosis and treatment of autism.Further reading: Machine learning to classify autism spectrum disorder will help open up precise treatment target researchAddresses:1.¬© All rights reserved Geneonline copyright No unauthorized reproduction. For cooperation, please contact:

Rewrite text Because autism is an individual disorder without precise standards, it is difficult to conduct quantitative research and treatment. In a review paper published in Molecular Psychiatry, the development of mouse models of human psychiatric disorders has proven to be a viable method for studying molecular mechanisms, along with a virtual reality system previously […]

Voice Actor Charles Martinet Retires After 32 Years as the Iconic Mario

Gaming Icon Charles Martinet Retires After 32 Years as the Voice of Super Mario In a surprising announcement, Charles Martinet, the legendary voice behind the iconic Super Mario character, has officially retired after an astonishing 32-year career. Nintendo, the company behind the beloved video game series, has confirmed the news, marking the end of an […]