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The Importance of Adult Vaccination and PCV13 Vaccination: Pfizer’s Webinar

Pfizer Pharmaceuticals Korea (CEO Dong-wook Oh) ​​announced on the 20th that it will hold a webinar on the topic of “Adult Vaccination and the Necessity of PCV13 Vaccination” for medical personnel on January 30th.

This webinar was held to highlight the importance of adult vaccination and to share the evaluation standards for pneumococcal conjugate vaccines, the distribution of pneumococcal serotypes in domestic adults, and the latest knowledge on vaccination based on real-world clinical evidence (RWE).

Pfizer Pharmaceuticals Korea announced on the 20th that it held a webinar on the topic of “adult vaccination and the need for PCV13 vaccination”.

Jinhan Kang, professor at the Vaccine-Bio Research Institute of the Catholic University of Korea, said: “In the past, importance was only given to vaccinations aimed at children, but now adults are no longer exempt from infectious diseases subject to vaccination.” , adding , “Changes in the epidemiology of infectious diseases, foreign travel and special occupations. He stressed: “While the need for vaccinations is gradually increasing due to various environmental changes, such as increased risk of exposure to infectious diseases due to work, and how we In an aging society, vaccination is emerging as an important public health problem for adults too”.

Professor Kang added that pneumococci are currently classified into approximately 90 serotypes based on their serotypic characteristics, and that there are differences in the serotypes that cause invasive pneumococcal infections depending on region, era, use of vaccines and age . Referring to the WHO report (Technical Report Series, No. 927, 2005), the superiority of a vaccine is not guaranteed unless there is evidence that the inclusion of additional serotypes is likely to improve its efficacy in a particular epidemiological context. judged solely on the number of serotypes identified,” he underlined.

Professor Kang said: “According to the results of surveillance of invasive pneumococcal pneumonia in domestic adults conducted by the Korea Agency for Disease Control and Prevention from September 2018 to June 2021, in the case of non-PCV13/PPSV23 serotypes, 10A, 11A/E and 15B are invasive: “It was the main serotype causing pneumococcal infection, and of the serotypes preventable with protein conjugate vaccines, 3 and 19A were the most commonly encountered,” he explained.

In the following presentation, the importance of actual clinical evidence in the evaluation of pneumococcal conjugate vaccines was shared. Professor Kang said: “Among the indicators evaluating vaccine efficacy, immunogenicity results alone are not sufficient to predict efficacy and effectiveness, and are confirmed through randomized controlled trials (RCTs) and Real World Evidence (RWE) “You need to look at both efficacy and effectiveness of the vaccine,” he suggested.

At the end of the presentation, the results of a study on the effectiveness of the 13-valent conjugated protein vaccine were also introduced, the effectiveness of which was confirmed through a real-world efficacy study. Prevenar 13 has been shown to reduce the risk of hospitalization due to community-acquired pneumococcal pneumonia (CAP) from the vaccine serotype by 72.8% in adults aged 65 years and older.

Song Chan-woo, vice president of Primary Care Division at Pfizer Korea, said: “Pfizer’s pneumococcal vaccine has confirmed its efficacy through real-world clinical trials that go beyond immunogenicity and include all prevalent national serotypes. “Based on these strengths, we have been ranked first in sales of pneumococcal vaccines in Korea for 14 consecutive years,” he said. “Pfizer Korea Pharmaceuticals prepared this vaccine for the first time in 2024 to share the latest knowledge on vaccination and pneumococcal infections.” vaccines with medical personnel.” “Starting from the webinar, this year we will always work hard to prevent and eradicate pneumococcal disease,” he said.

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