“This ingredient in red ginseng kills colon cancer cells without toxicity.”
- Research results have been published showing that red ginseng inhibits the growth of colon cancer cells and helps maintain bone and intestinal health by balancing intestinal microorganisms.
- At the Korean Ginseng Society Fall Academic Conference held at the Maison Glad Jeju Hotel in Jeju Island from the 27th to the 30th, researchers from Korea, China,...
- The Rh2 component of red ginseng has been found to safely inhibit the growth of colon cancer cells.
Kyungpook National University Department of Animal Biotechnology and Professor Kim Myeong-ok’s team presented at the fall conference of the Korean Ginseng Society.
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Research results have been published showing that red ginseng inhibits the growth of colon cancer cells and helps maintain bone and intestinal health by balancing intestinal microorganisms. [사진=클립아트코리아]
Research results have been published showing that red ginseng inhibits the growth of colon cancer cells and helps maintain bone and intestinal health by balancing intestinal microorganisms.
At the Korean Ginseng Society Fall Academic Conference held at the Maison Glad Jeju Hotel in Jeju Island from the 27th to the 30th, researchers from Korea, China, Japan, and the United States gathered to discuss △the principle of red ginseng in inhibiting the growth of colon cancer △intestinal health through the balance of intestinal microorganisms. Research results on a total of 30 topics were presented, including contribution to bone health, cancer treatment effects, and respiratory virus immunity effects.
The Rh2 component of red ginseng has been found to safely inhibit the growth of colon cancer cells.
First, the research team of Professor Myeong-ok Kim of the Department of Animal Biotechnology and Professor Jae-woong Ryu of the Department of Biotechnology at Kyungpook National University found that the Rh2 component of red ginseng inhibits the proliferation, migration, and invasion of colon cancer cells, induces the death of colon cancer cells, and interacts with the AXL (cancer targeting protein) receptor that activates cancer cells. The process of directly binding and inhibiting the signaling pathway was identified for the first time.
In addition, it was confirmed through animal experiments that Rh2 suppresses colon cancer tumor growth. In particular, the Rh2 component is significant in that it safely suppresses cancer cells without toxicity, unlike existing anticancer treatments.
It is known that existing chemotherapy for the treatment of colon cancer has difficulties in treating cancer as the longer the administration period, the less effective it is due to anticancer drug resistance and the occurrence of various side effects such as cardiovascular disease.
Professor Kim Myeong-ok’s team said, “Through the results of this study, we expect to develop a safe new drug based on natural products that can reduce side effects from anti-cancer treatment and provide more fundamental treatment.” This study was published in the ‘Journal of Ginseng Research’ and received an academic encouragement award from the Korean Ginseng Society.
Red ginseng helps prevent bone loss and leaky gut syndrome due to intestinal microbial imbalance
Professor Parameswaran of Michigan State University is giving a presentation at the fall conference of the Korean Ginseng Society. [사진=고려인삼학회 제공]
It has also been found that red ginseng extract helps balance intestinal microorganisms. Professor Narayanan Parameswaran’s team from the Department of Physiology at Michigan State University, USA, identified and announced that bone loss and leaky gut syndrome can be prevented through this information.
When the research team administered antibiotics to a mouse model for two weeks and observed it for four weeks, it was confirmed that an imbalance occurred in the composition of intestinal microorganisms, leading to leaky gut syndrome and bone loss. Leaky gut syndrome is a condition in which the intestinal mucosa cells are damaged and the barrier is weakened, allowing various substances to pass in and out, and is accompanied by symptoms such as gas, diarrhea, constipation, abdominal bloating, and indigestion.
The research team administered antibiotics (800mg/kg/day) to mice for 2 weeks, then divided them into two groups. One group consumed red ginseng (500mg/kg/day) for 4 weeks, and the other group received only antibiotics. did it As a result, it was confirmed that in the red ginseng administered group, the number of cancellous bone marrow increased in the femur, the cancellous bone gap decreased, and the volume of the femur increased. In addition, only the red ginseng group showed that various beneficial bacteria in the intestinal microflora were enriched. In terms of permeability within the intestinal wall, leaky gut syndrome increased in the antibiotic group, while leaky gut syndrome significantly decreased in the red ginseng group.
Professor Parameswaran said, “It is significant that we confirmed the probiotic effect of red ginseng and its potential for development as a treatment for osteoporosis in the future.”
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