TRIMTECH Therapeutics Appoints Dr Mike Hutton to Scientific Advisory Board
TRIMTECH Therapeutics Appoints Dr. Mike Hutton too Scientific Advisory board
TRIMTECH Therapeutics announced the appointment of Dr. Mike Hutton to its Scientific Advisory Board (SAB). dr. Hutton brings decades of experience in neurodegenerative disease research and drug growth, aiming to accelerate the company’s mission to create accessible, disease-modifying treatments.
Dr. Mike Hutton’s Extensive Background
Dr.Hutton most recently served as Chief Scientific Officer (CSO) and Vice president of Neurodegeneration Research and UK Site Scientific leader at Eli Lilly and Company. In these roles,he spearheaded drug discovery efforts for Alzheimer’s Disease,Parkinson’s Disease,and fronto-temporal dementia. Prior to Eli Lilly, he held a Senior Director position at MSD (Merck Sharp & Dohme) and was a Consultant and Professor of Neuroscience at the Mayo Clinic.
At the Mayo Clinic,Dr. Hutton’s research team made meaningful contributions to identifying the genetic causes of fronto-temporal dementia,including pinpointing mutations in the tau and progranulin genes. His work on tau protein earned him both the Potamkin Prize and the MetLife Prize – prestigious awards recognizing outstanding contributions to the understanding of neurodegenerative diseases. He holds a BSc in Biochemistry from the University of Manchester and a PhD in Neuroscience from the University of Cambridge.
About the Potamkin Prize and MetLife Prize: The Potamkin Prize, awarded by the American Academy of Neurology, recognizes individuals who have made significant contributions to the understanding of human neurological diseases.The MetLife Foundation Award for Research in Alzheimer’s Disease, now the Zenith Award, similarly honors researchers making impactful discoveries in Alzheimer’s disease.
“We’re delighted to welcome Mike as the newest member of our recently formed Scientific Advisory Board. his extensive expertise in neurodegenerative disease therapeutics will be a great asset as we continue to advance our mission to deliver first-in-class medicines to address the critical need for cost-effective, disease-modifying treatments for neurodegeneration that can reach broad patient populations.”
Dr. nicola Thompson, CEO, TRIMTECH Therapeutics
Dr. Hutton expressed his enthusiasm for TRIMTECH’s innovative approach, stating: “TRIMTECH’s novel approach is leading the way in the development of small molecule CNS penetrant degraders for neurological disorders, addressing the difficult to drug targets underpinning these diseases.I am delighted to join the SAB – the Company has assembled an excellent team, and I look forward to helping guide the development of these much-needed, accessible therapeutic options.”
TRIMTECH’s Focus on CNS Penetrant Degraders
TRIMTECH Therapeutics is focused on developing small molecule drugs that can cross the blood-brain barrier (CNS penetrant) and selectively degrade disease-causing proteins. This approach aims to tackle neurological disorders by targeting previously “undruggable” targets, offering potential for more effective and accessible treatments. The company’s strategy centers on creating therapies that modify the course of neurodegenerative diseases, rather than simply managing symptoms.
Understanding CNS Penetration: The blood-brain barrier (BBB) is a highly selective semipermeable border of endothelial cells that prevents solutes in the circulating blood from non-selectively entering the central nervous system (CNS), where the delicate brain tissue resides. Developing drugs that can effectively cross the BBB is a major challenge in neurological drug development.
This article was last updated on November 13, 2023, at 04:21:40 UTC.
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