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Beyfortus vs. Abrysvo: A Detailed Comparison for Bronchiolitis Prevention
Table of Contents
Understanding Bronchiolitis and RSV
Bronchiolitis is an inflammation of the small airways in the lungs, most commonly caused by the respiratory syncytial virus (RSV). It primarily affects infants and young children, leading to symptoms like coughing, wheezing, and difficulty breathing. In severe cases, hospitalization may be required.
RSV is highly contagious and spreads through respiratory droplets. While most children recover fully, bronchiolitis can be notably dangerous for infants with underlying health conditions, such as premature birth or congenital heart disease.
Beyfortus (Nirsevimab): A Monoclonal Antibody
Beyfortus is a monoclonal antibody that provides passive immunity against RSV. Unlike a vaccine, it doesn’t require the body to mount an immune response. Rather, it directly provides antibodies to neutralize the virus. This makes it suitable for all infants, even those with weakened immune systems.
- Mechanism: Provides immediate protection by supplying pre-formed antibodies.
- Administration: A single intramuscular injection.
- Duration of Protection: Protection lasts for approximately 5 months, covering a typical RSV season.
- Target Population: All infants, particularly recommended for those at high risk of severe RSV disease.
Abrysvo (RSV Vaccine): An Active Immunization
Abrysvo is an RSV vaccine designed to stimulate the mother’s immune system during pregnancy, creating antibodies that will be passed on to the baby, providing protection after birth. it’s also approved for older adults.
- Mechanism: Stimulates the mother’s immune system to produce antibodies against RSV.
- Administration: A single dose administered during pregnancy (typically between 32 and 36 weeks gestation).
- Duration of Protection: Protection is expected to last for
