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“Corona 19 vaccination reduces the risk of cardiovascular side effects after infection” : Donga Science

On the 11th, at a pediatric clinic in Gangnam, Seoul, a man in his 60s or older is vaccinated with Spikebox, a newly updated bivalent vaccine for Corona 19 from Moderna. Provided by Yonhap News

A research team in the United States released the result of an analysis that showed that those who had been vaccinated against the new coronavirus infection (COVID-19, Corona 19) had a relatively lower risk of experiencing “major adverse cardiac events (MACEs).” such as stroke and myocardial infarction.

The research team led by Girish Nadkarni, a professor at Mount Sinai University School of Medicine, USA, published the findings in the international journal ‘Journal of the American Heart Association’ on the 20th (local time). As a result of a large-scale analysis of 1,934,294 patients with Corona 19, this is the first study to investigate the link between vaccination with Corona 19 and major abnormal reactions of the heart.

The research team used the ‘N3C’ database, the largest database in the US related to COVID-19. They found that 217,843 of all Corona 19 patients were vaccinated with the US Pfizer, Modena, and Janssen vaccine.

As a result of their analysis, patients who completed two doses of the vaccine had a 59% lower chance of experiencing a major adverse heart reaction than those who did not receive the vaccine. The research team said, “Evidence shows that vaccination against Corona 19 helps reduce the risk of complications after Corona 19 infection.”

A Korean research team has also presented similar findings. A research team led by Professor Jeong Jae-hoon of Gachon University’s School of Preventive Medicine and Professor Heo Kyung-min of Infectious Medicine at Samsung Hospital Seoul reported in the Journal of the American Medical Association (JAMA) in June last year that the probability of myocardial infarction in those infected with Corona 19 without vaccination was 6.18 per 1 million people. On the other hand, the group that completed vaccination was 5.49 per 1 million people. For stroke alone, the incidence rate in the unvaccinated group was 4.59 per 1 million people and 3.71 in the vaccinated group.

Professor Nadkarni said, “I hope the results of this study will help improve the global vaccination rate,” and “we will conduct additional research to reveal the associated mechanism from an immunological perspective.”

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