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Dr. Anan reveals that Omikron BA.2 is a mutant! inactivation of antibodies

Dr Anan said very few of the antibodies to date still bind and inhibit omikron, although they are less effective compared to other strains, such as sotrovimab, which were tested as hope. of Omicron treatment That’s good news.

But the bad news is that Omikron, the BA.2 strain, which has been changed in some places from BA.1, appears to inactivate this antibody.

The results of the recently released test are The value at which the drug inhibited the virus from entering cells was 50% (IC50) from 2072 ng/ml in the Omicron strain BA.1.

But the values ​​were too high when tested against BA.2, suggesting that the antibody might not be effective against BA.2, as well as Evushield, another formulation of the antibody. Additional new antibodies may be needed to counteract BA.2.