Heavy Drinking and Alzheimer’s: Brain Inflammation & Protein Damage
Okay, here’s a breakdown of the abbreviations used in the provided text, along with their full names:
* AD: Alzheimer’s Disease
* AUD: Alcohol Use Disorder
* ROS: Reactive Oxygen Species
* SOD: Superoxide Dismutase
* GPx: Glutathione peroxidase
* TLR4: Toll-Like Receptor 4
* NF-κB: Nuclear Factor kappa B
* Nrf2: Nuclear factor erythroid 2-related factor 2
* HO-1: Heme Oxygenase 1
* GABA: Gamma-aminobutyric acid
* GSK-3β: Glycogen Synthase Kinase-3 beta
* JNK: c-Jun N-terminal Kinase
* Aβ: Amyloid-beta
* BACE1: Beta-site Amyloid Precursor Protein Cleaving Enzyme 1
* IDE: insulin-Degrading Enzyme
* LRP1: Low-Density Lipoprotein Receptor-Related Protein 1
* p38 MAPK: p38 Mitogen-Activated Protein Kinase
* MAPK: mitogen-activated Protein Kinase
* IIA: (Part of tanshinone IIA, a compound)
* ALDH2: Aldehyde Dehydrogenase 2
* Duolac ProAP4: A specific probiotic strain.
This list should cover all the abbreviations used in the text. Let me know if you’d like any further clarification or have another text you’d like me to analyze!
