A Comparative Analysis of Adverse Reactions: Corona Vaccine vs. Flu Vaccine
Risk of Adverse Effects Found to be Higher in Rheumatism Patients
A recent report on the safety of the corona vaccine has raised concerns regarding its impact on rheumatism patients. In comparison to the flu vaccine, it appears that these patients experience more adverse effects.
A study, published in the Journal of Korean Medical Science, conducted a thorough analysis to compare the reactions caused by the corona vaccine and the flu vaccine specifically in rheumatoid patients. The results shed light on the risks associated with these vaccinations.
Despite the ongoing pandemic and the increasing number of COVID-19 cases, the demand for corona vaccines and diagnostic kits continues to surge. Patients with autoimmune diseases, such as rheumatism, were recommended to receive vaccinations. However, the lack of concrete evidence on the vaccine’s effectiveness on these individuals has raised doubts.
Safety concerns surrounding the corona vaccine have also emerged due to its swift approval and administration. This prompted Professor Kim Hyun-ah from Ajou University Medical School to lead a research team in Korea to conduct a study on rheumatism patients who had already received the corona vaccine.
The objective of the study was to compare the effects of the corona vaccine to that of the flu vaccine, which is already administered to a large number of patients, in order to identify potential risks.
Analysing Adverse Reactions of Corona and Influenza Vaccines
The research team analyzed 601 rheumatism patients who had received the corona vaccine, comparing their clinical outcomes with those who had received the flu vaccine.
The analysis revealed that 42.4% of the patients completed their first corona vaccine dose, with 56.9% receiving an additional vaccination. The Pfizer vaccine was administered to 61.4% during the first dose, while subsequent doses consisted of 83.3% Pfizer and 16.4% Moderna.
When examining adverse reactions, it was found that 52.2% of rheumatism patients who received the corona vaccine experienced adverse effects. This is considerably higher compared to the 5.8% observed in flu vaccine recipients.
The most common adverse reactions reported were muscle pain (27.5%), sudden fatigue (20.8%), headache (18.1%), and fever (17.5%). However, no significant difference in reaction rates was observed between different vaccine brands.
While most patients experienced no complications after receiving the flu vaccine, 7.5% of patients sought medical assistance for adverse reactions to the corona vaccine. Additionally, 2.2% were admitted to the emergency room.
Higher Risk of Disease Activation with Corona Vaccine
Furthermore, the study revealed a significantly higher rate (16.2%) of disease activation in well-controlled rheumatic patients who received the corona vaccine. This rate was more than 10 times higher than that observed with the flu vaccine (1.4%).
Alarmingly, 80% of patients experienced disease activation within three days of receiving the corona vaccine, leading 67.2% to seek medical attention.
The research team emphasized, “The study findings demonstrate a substantially higher rate of disease activation among rheumatism patients who received the corona vaccine, which poses a significant concern. This study stands as a crucial contribution, being the first to compare adverse reactions and disease activation rates between flu and corona vaccinations.”
Despite the report that the corona vaccine is relatively safe, it seems that the actual rheumatism patients have more adverse effect than the flu vaccine.
This is because the rate of adverse reactions and the rate of disease activation, that is, the risk of recurrence of rheumatoid disease, is more than 10 times higher than when receiving a flu vaccine.
A study was published comparing the adverse reactions between the corona vaccine and the flu vaccine.
On the 14th, the Journal of Korean Medical Science, an international academic journal of the Korean Medical Association, will publish the results of a comparative analysis of the effects of corona vaccine and flu vaccine on rheumatoid patients.
Despite the current endemic trend, as the number of corona patients continues to increase, the demand for corona vaccines, including diagnostic kits, is steadily increasing.
During the corona pandemic, it was recommended that patients with autoimmune diseases, such as rheumatism patients, benefit from being vaccinated, but the reality is that there is not enough evidence on the actual effect on these patients.
In particular, as the corona vaccine is approved and administered at an unprecedentedly fast pace, doubts about safety remain.
This is also the background for the research team led by Professor Kim Hyun-ah from Ajou University Medical School to conduct a study on rheumatism patients who actually received the corona vaccine in Korea.
Its purpose is to compare the effect of the corona vaccine on patients compared to the flu vaccine, which many patients already receive, to identify the risks.
Accordingly, the research team compared and analyzed the difference in clinical prognosis when vaccinated with the flu vaccine for 601 rheumatism patients who were vaccinated with the corona vaccine.
Comparative analysis of corona vaccine and influenza vaccine adverse reactions
As a result of the analysis, 42.4% of 601 patients completed the first vaccination and 56.9% received an additional vaccination.
The first vaccination was 61.4% with the Pfizer vaccine, and additional vaccinations were also confirmed at 83.3%, Pfizer and Modena at 16.4%.
When comparing adverse reactions after vaccination, 52.2% of rheumatism patients who received the corona vaccine were found to have adverse reactions. This is quite high compared to only 5.8% after getting the flu vaccine.
In terms of adverse reaction rates, muscle pain was the most common at 27.5%, followed by sudden fatigue at 20.8%, headache at 18.1%, and fever at 17.5%. However, there was no significant difference among vaccine producers.
In addition, most of the patients passed without problems regarding adverse reactions after being vaccinated against influenza, but 7.5% of patients visited an outpatient clinic due to adverse reactions to the corona vaccine, and 2.2% were in the hospital in the emergency room.
The rate of disease activation, that is, reactivation of well-controlled rheumatic diseases, was also much higher with the corona vaccine.
This is because the activation rate of the disease after receiving the corona vaccine was 16.2%, which was more than 10 times higher than the flu vaccine (1.4%).
Specifically, 80% of patients were counted as 67.2% of patients found a medical institution as the disease was activated within 3 days after the corona vaccine.
The research team said, “As a result of the study, rheumatism patients who received the corona vaccine had a significantly higher rate of disease activation, a very important problem, compared to the flu vaccine.”
“It is meaningful as this is the first study to compare adverse reactions and disease activation rates between flu and corona vaccinations,” he said.
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