INEGI Reveals Top Causes of Death in Mexico for 2025

Heart disease, diabetes, and tumors remained the three leading causes of death in the country, though overall mortality rates returned to levels seen before the COVID-19 pandemic, according to reporting from Reforma and Jornada.

The INEGI figures indicate a downward trend in total deaths compared to the spikes seen during the pandemic years. This shift suggests a stabilization of the national health profile, with mortality figures aligning with pre-pandemic baselines, according to Reforma.

Heart diseases continue to be the primary cause of death in Mexico. This is followed by diabetes mellitus and malignant neoplasms, or tumors, which consistently rank as the top three drivers of mortality according to data analyzed by El Financiero and UnoTV.

Leading Causes of Death in Mexico for 2025

The INEGI report identifies a concentration of deaths within non-communicable diseases. Heart diseases remain the most frequent cause of death, reflecting ongoing challenges with cardiovascular health across the population, according to El Financiero.

Diabetes mellitus remains the second leading cause of death.

Tumors and cancer rank as the third leading cause of death. The data highlights the persistent impact of oncological diseases on the national mortality rate, according to INEGI.

Regional Variations in Mortality Rates

Mortality rates vary significantly by state. Nuevo León recorded the second lowest death rate in Mexico during 2025, according to reports from Milenio.

This regional data suggests that while national trends are dominated by chronic diseases, certain states are experiencing lower overall mortality frequencies than the national average, according to Milenio.

Comparison to Pandemic-Era Data

The 2025 total of 762,494 deaths represents a notable decline from the peak years of the COVID-19 health crisis. Reforma reports that these numbers have now reached pre-pandemic levels, marking a return to historical norms for the country’s death toll.

While the total number of deaths has decreased, the underlying causes have remained stable. The dominance of heart disease, diabetes, and cancer indicates that the primary health threats to Mexicans are chronic conditions rather than acute infectious outbreaks, according to the INEGI data cited by El Financiero.