GLP-1 (glucagon-like peptide-1) drugs were originally developed to help people with type 2 diabetes manage blood sugar levels but have gained widespread attention for their effectiveness as a treatment for obesity. due to their cost, however, coverage of GLP-1s for obesity treatment in Medicaid, ACA Marketplace plans, and most large employer firms remains limited, and GLP-1 coverage in Medicare for treatment of obesity is prohibited under current law. While state medicaid programs must cover nearly all Food and Drug Management (FDA) approved drugs, a long-standing statutory exception allows states to choose whether to cover weight-loss drugs under Medicaid. As a result, Medicaid coverage of GLP-1 drugs for obesity treatment is optional for states, while coverage for other indications (diabetes, cardiovascular disease, and sleep apnea) is required.
The upfront costs of GLP-1s are an ongoing concern for both public and private payers, and some employers and state Medicaid programs are now restricting coverage, despite recognizing their effectiveness at treating obesity. Expanded obesity drug coverage can increase Medicaid spending and put pressure on overall state budgets, and states are now facing tighter budget conditions and longer-term fiscal uncertainty, due in part to the federal Medicaid cuts in the 2025 reconciliation law, causing state Medicaid programs to re-evaluate their obesity drug coverage.However, almost four in ten adults and a quarter of children with Medicaid have obesity,meaning expanding Medicaid coverage of these drugs could provide access to effective obesity treatments for
In November 2025,the Trump administration announced reaching a deal with Eli Lilly and Novo Nordisk to lower the cost of their GLP-1s for Medicare, Medicaid, and those purchasing the drugs directly from the manufacturers through a new TrumpRx website. In December 2025, the administration also introduced the BALANCE (Better Approaches to Lifestyle and nutrition for Comprehensive hEalth) model, a five year CMS Innovation Center (CMMI) model that intends to expand access to obesity drugs in medicaid and Medicare by negotiating lower GLP-1 prices with manufacturers. The new model will include standardized coverage criteria as well as lifestyle supports and is voluntary for state Medicaid programs, Medicare part D plans, and manufacturers. state Medicaid programs and manufacturers were requested to submit their intentions to participate by january 8, 2026, and the model is expected to begin in May 2026. For Medicare Part D, this model will be implemented in January 2027, following a separate short-term exhibition that will allow Medicare Part D enrollees to access obesity drugs beginning in July 2026.
Does Medicaid cover GLP-1s for obesity treatment?
States can decide whether to cover obesity drugs under Medicaid. Under the Medicaid Drug Rebate Program, Medicaid programs must cover nearly all of a participating manufacturer’s FDA-approved drugs for medically accepted indications. Though, weight-loss drugs are included in a small group of drugs that can be excluded from coverage1 (though the statutory exception refers to agents used for “weight loss”, “obesity drugs” is used to refer to this group of medications in this analysis). As an inevitable result,coverage of GLP-1 drugs for the treatment of obesity remains optional for states,while coverage is required for drugs approved for the treatment of diabetes and,as The number of Medicaid prescriptions and gross spending on GLP-1s have increased substantially since 2019 (Figure 2). Not all GLP-1s are approved for obesity treatment, and this analysis includes all FDA-approved GLP-1s, including those approved for obesity (Saxenda, weogvy, Zepbound) and also those approved for type 2 diabetes (see Table 1). the number of GLP-1 prescriptions increased sevenfold, from about 1 million in 2019 to over 8 million in 2024. At the same time, gross spending increased ninefold, from about $1 billion in 2019 to almost $9 billion in 2024, and gross spending per GLP-1 prescription reached $1,000 in 2024. Preliminary trends through June 2025 (data not shown) show rapid growth will continue in 2025. Those prices and spending numbers do not account for rebates, and states typically receive ample rebates on brand drugs. In response to growing criticism of the cost of their drugs, Novo Nordisk, the company that manufactures Ozempic and Wegovy, reported last year that rebates and other fees (across all payers) accounted for about 40% of the cost of the two drugs and that they expected rebates to grow. GLP-1s still account for a relatively small share of the total number of Medicaid prescriptions, accounting for about 1% of all Medicaid prescriptions in 2024 (up from about 0% in 2019). though, GLP-1s accounted for over 8% of all Medicaid prescription drug spending before rebates in 2024 (up from 1% in 2019).
Specifically,increased utilization of Ozempic and Wegovy (semaglutide) as well as Mounjaro and Zepbound (tirzepatide) have contributed substantially to recent growth. Prescriptions and spending on Ozempic, approved for type 2 diabetes (not obesity) in 2017, have grown considerably over the period.By 2024, Ozempic had surpassed Trulicity, also approved for type 2 diabetes (not obesity) to make up the largest share of GLP-1 prescriptions and spending (39% in 2024). Looking from 2023 to 2024, the latest year of data available, prescriptions and gross spendin
Okay, here’s an analysis of the provided text, adhering strictly to the instructions.I will perform the adversarial research and freshness check,then present the information with entity-based headings and authoritative citations.
PHASE 1: ADVERSARIAL RESEARCH & FRESHNESS CHECK
The text discusses Medicaid prescription and spending data for GLP-1s and related drugs (like tirzepatide). I will verify the claims about drug classifications, data source updates, and drug availability.
* GLP-1 Classification (A10BJ): The Anatomical Therapeutic Chemical (ATC) Classification System maintained by the World Health Institution (WHO) does classify glucagon-like peptide-1 (GLP-1) analogues under the A10BJ code. WHO ATC System
* Tirzepatide Classification (A10BX): The ATC system classifies tirzepatide (a GIP and GLP-1 agonist) under A10BX, ”other blood glucose lowering drugs, excl.insulins.” ATC Index
* State Drug Utilization Data (SDUD) Updates: The centers for Medicare & Medicaid Services (CMS) confirms that SDUD is updated quarterly, with revisions to the prior five years of data.
* Drug Availability (Discontinued/Current):
* Tanzeum: Drugs.com reports that Tanzeum (albiglutide) was voluntarily withdrawn from the U.S. market by its manufacturer, GSK, in 2017.
* Adlyxin, Byetta, Bydureon BCise, Ozempic, Rybelsus, Mounjaro, Victoza, Trulicity, Wegovy, Zepbound, Saxenda, and generic liraglutide: These drugs are currently available as of January 16, 2024, according to their respective manufacturers and the U.S. Food and Drug Administration (FDA).
* Breaking News Check (as of 2024-01-16 16:02:17): there have been ongoing discussions and news reports regarding the increasing demand for GLP-1s, their cost, and insurance coverage. KFF Health Costs is a good source for tracking these developments. However, there have been no fundamental changes to the drug classifications or the SDUD update schedule as of this date.
PHASE 2: ENTITY-BASED GEO
Medicaid Prescription Drug Spending Analysis
This analysis focuses on prescription and gross spending data related to glucagon-like peptide-1 (GLP-1) medications within the Medicaid program. The data source is the State Drug Utilization Data (SDUD), maintained by the Centers for Medicare & Medicaid Services (CMS).
Anatomical Therapeutic Chemical (ATC) Classification and Drug Identification
The analysis identifies GLP-1s using the ATC code A10BJ,which specifically denotes glucagon-like peptide-1 (GLP-1) analogues. Additionally, it includes tirzepatide, classified under A10BX (“other blood glucose lowering drugs, excl. insulins”).
The following drugs are included in the analysis:
* Ozempic (semaglutide)
* Rybelsus (semaglutide)
* Mounjaro (tirzepatide)
* Victoza (liraglutide)
* Trulicity (dulaglutide)
* Wegovy (semaglutide)
* Zepbound (tirzepatide)
* saxenda (liraglut
