Ozempic, Wegovy & Co.: Celebrity Side Effects
- Reports of side effects, including hair loss and "Ozempic face," are becoming more prominent as weight loss injections gain popularity.
- Rapid weight loss can have unintended consequences for the body, some of which may only be revealed in long-term studies.
- Ozempic, Wegovy, and similar medications are gaining traction as weight loss aids.
Weight Loss Injections: The Unintended Consequences
Reports of side effects, including hair loss and “Ozempic face,” are becoming more prominent as weight loss injections gain popularity.
Rapid weight loss can have unintended consequences for the body, some of which may only be revealed in long-term studies.
Published: May 3, 2025, 7:26 PM

- Weight loss injections,such as ozempic,can cause unwanted side effects.
- Reported side effects include nausea, diarrhea, sagging skin, and changes in blood pressure.
- Researchers warn of a potential increased risk of pancreatitis.
Ozempic, Wegovy, and similar medications are gaining traction as weight loss aids. These injections contain semaglutide, an active ingredient typically prescribed for patients with Type 2 diabetes. Semaglutide activates GLP-1 receptors throughout the body, affecting the brain, gastrointestinal tract, pancreas, and cardiovascular system. While it can lead to satiety, reduced blood sugar, and weight loss, it also carries the risk of various systemic side effects.
Nausea: A Common side Effect
Semaglutide slows gastric emptying, which can initially aid weight loss by suppressing hunger. However, in some instances, the gastric muscles slow down excessively, hindering proper stomach emptying. This can disrupt healthy digestion, causing food to remain in the stomach for too long, leading to feelings of fullness, bloating, and discomfort.
American comedian Amy Schumer reported losing 13 kilograms (29 pounds) with Ozempic but discontinued the medication after a few weeks due to the unpleasant side effects.
Lottie Moss, sister of supermodel Kate Moss, reported a trip to the emergency room. She self-administered the medication and complained of nausea and vomiting, and claimed to have a seizure. Doctors attributed her condition to a severely reduced calorie intake, resulting in a lack of energy and protein, leading to muscle breakdown and undersupply.
The “Ozempic Face” and Skin Consequences
Facial surgeons in the United States have noted an increase in clients seeking treatment related to Ozempic use. According to surgeon Jason Diamond, patients are primarily seeking to tighten excess tissue after weight loss. Diamond told American media last summer that the skin of Ozempic patients resembles an “overstretched rubber band,” appearing substantially thinner and weaker than normal.
The skin can appear older and sag, particularly around the jawline. The loss of subcutaneous fat makes veins, tendons, bones, and muscles more prominent. This phenomenon has been dubbed “Ozempic Face” or “Ozempic Feet” in Hollywood.
Speculation arose regarding whether Sharon Osbourne, manager and wife of Black Sabbath singer Ozzy Osbourne, and talk show host Oprah Winfrey had used Ozempic. Diamond also noted a growing trend of patients seeking fillers to restore volume in areas affected by weight loss.
Weight Loss Injections: Your Questions Answered
What are weight loss injections, and why are thay gaining popularity?
Weight loss injections, such as Ozempic and Wegovy, are medications designed to aid in weight loss. Their increasing popularity stems from their potential to help people loose weight and improve their health,especially for those with conditions like Type 2 diabetes.These injections contain semaglutide, an active ingredient that affects various systems in the body.
How do weight loss injections work?
The active ingredient, semaglutide, found in medications like Ozempic and Wegovy, activates GLP-1 receptors throughout the body. This affects the brain, gastrointestinal tract, pancreas, and cardiovascular system. Semaglutide can lead to reduced blood sugar levels, feelings of fullness (satiety), and consequently, weight loss.
What are the reported side effects of weight loss injections?
Reports of side effects are becoming more common as these injections gain popularity. Some of the reported side effects include:
- Nausea
- Diarrhea
- Sagging skin
- Changes in blood pressure
- Potential increased risk of pancreatitis (according to researchers)
- Hair loss
Why does nausea occur with weight loss injections?
Semaglutide can slow gastric emptying,which means food stays in the stomach longer. While this can initially lead to weight loss by suppressing hunger, it can also cause:
- Feelings of fullness
- Bloating
- Discomfort
- Nausea
- Vomiting
American comedian Amy Schumer reported experiencing unpleasant side effects and discontinued the medication due to these problems. Lottie Moss also reported a trip to the emergency room due to nausea, vomiting, and a claimed seizure after self-administering the medication.
What is “Ozempic Face,” and why does it happen?
“Ozempic Face” is a term used to describe a change in facial appearance some people experience after significant weight loss, notably with medications like Ozempic. This is because of fat loss in the face, which makes the skin appear thinner, and can cause it to sag. this phenomenon is related to the loss of subcutaneous fat, making veins, tendons, bones, and muscles more prominent. Facial surgeons in the United States have noted an increase in clients seeking treatments to address this issue.
Are there long-term consequences of rapid weight loss with these injections?
Rapid weight loss can have unintended consequences, some of which may only be revealed in long-term studies. Researchers have warned of potential risks, such as pancreatitis. The full extent of the long-term effects is still being investigated.
Who has spoken about their experiences with weight loss injections?
Amy Schumer has spoken about her experience with weight loss injections. Others, such as Lottie Moss, have also shared their experiences, highlighting the potential side effects of these medications.
Are there any celebrity connections to these weight loss injections?
Speculation has arisen regarding whether Sharon osbourne and Oprah Winfrey have used Ozempic. While these reports remain unconfirmed, they highlight the growing interest in these treatments.
What are the most common weight loss injections?
Ozempic and Wegovy are two of the most commonly discussed weight loss injections. They both contain semaglutide.
What are the key differences between Ozempic and Wegovy?
While both Ozempic and Wegovy contain semaglutide, they have different primary uses and dosages. As this information isn’t directly available in the content, please consult a healthcare professional for a comparison.
Summary Table: Key Points
here’s a summary of key facts about weight loss injections based on the provided content:
| Feature | Details |
|---|---|
| Active Ingredient | Semaglutide |
| Primary use | Weight Loss (Wegovy), Type 2 Diabetes (Ozempic) |
| Mechanism | Activates GLP-1 receptors; reduces blood sugar; promotes satiety. |
| Common Side Effects | Nausea, diarrhea, sagging skin, potential pancreatitis risk. |
| Notable Side Effect | “Ozempic Face” (facial skin changes due to fat loss) |
| Reported Experiences | amy Schumer, lottie Moss (emergency room visit) |
