Department of Science launches digital platform ‘Phoopphan’ to report pharmacogenetic test results. “Severe drug allergy genes” of 4 types, including gout medicines, anticonvulsant medicines, HIV medicines, and tuberculosis medicines, provide information for doctors and pharmacists to choose medicines and plan treatment appropriate for patients. Preventing Severe Allergic Reactions to Drugs People can check the information.
On February 21, Dr. Yongyot Thamwut, director general of the Department of Medical Sciences, together with Dr. Banlang Uphong, deputy director general of the Department of Medical Sciences and Dr. Panadda Thepaksorn, director of the Institute of Medical Biosciences. Department of Medical Sciences Press conference for the launch of the digital platform “Phoekphet”, which links genetic information to precise treatment. In collaboration with Mahidol University
Dr. Yongyot said testing for drug allergy genes is important. The detection rate of drug allergy genes in Thais was found to be 15%, or 9.7 million people, and was found in 42,000 – 100,000 patients. It will reduce the occurrence of severe drug allergic skin rashes, drug allergies, reduce the mortality rate by more than 90%, and help save the country’s budget for medical treatment of patients with severe drug allergies by more than 250 million baht per year. Therefore, the Department created a digital platform system “Bybreeding” to report the results of genetic tests on patients. and evaluate the possibility of a severe drug allergy in the patient. What are the possibilities? Pharmacogenetic testing will allow the treating doctor to choose the drug or adapt the dosage appropriate for the patient. It makes it safe from drug allergies. The results of a single test can be used for a lifetime. Doctors, pharmacists and patients can view the results of their genetic tests from the department’s laboratory.
Dr Yongyot said that in 2023, the department will open pharmacogenetic testing services to the public. To prevent serious drug allergies, the 4 tests are: 1. Check the HLA-B*58:01 gene for patients receiving uric acid-lowering drugs, allopurinol (Allopurinol), or drugs to treat gout. 2 HLA-B*15:02 gene testing for patients receiving the anticonvulsant drug carbamazepine. (Carbamazepine) 3. Test the HLA-B*57:01 gene in a group of patients receiving the antiretroviral drug Abacavir (Abacavir) and 4. Test the NAT2 drug subgene in tuberculosis patients who received the drug Isoniazid. The Department hopes that “Tiemphun” will be a good starting point for medical treatment. It helps doctors use information to plan disease prevention and treatment more specifically and accurately, and in 2024 will expand the use of the “Pupphant” digital platform system to connect hospital information systems to access pharmacogenetic test results .
Dr Banlang said the use of “Phoengphan” requires the user to enter personal data. and confirm your identity in the system registration process To ensure the safety of patient information Users are divided into 3 types: 1. Citizens can access information about their test results. 2. Doctors and pharmacists You can access information about your test results by searching for information by your ID card number. o first and last name Additionally, data access requests must be sent to the owner of the data before he or she can view it. And 3. Laboratory personnel are the ones who report test results into the system. In addition, it can support displaying test result data on personal electronic health record application such as Doctor Prom, Health Link, etc., allows people to access information about their pharmacogenetic test results. Reduce costs resulting from redundant inspections and the cost of treatment in case of a severe allergic reaction. Including linking data with the hospital information system, allowing test results to be sent to the hospital system, but must first receive patient consent.
“Tie Phi” is a means of accessing genetic test results. and facilitate medical staff in quickly and accurately accessing test results, helping patients to independently access test results. It is a platform that supports both formats of websites. and smartphone applications, both iOS and Android systems: just register and verify your identity via ThaiD online ID card and you will be able to access your test results.
Dr Panadda said genetic testing for drug allergy is currently included in the benefits of the 30 baht gold card system, social security and medical benefits of civil servants. They are patients with indications according to the doctor’s opinion. It can be sent for examination at the Department i.e. Institute of Medical Biosciences. And in the region, there are 14 medical science centers across the country, including Chiang Mai, Chiang Rai, Phitsanulok, Nakhon Sawan, Samut Songkhram, Chonburi, Khon Kaen, Udon Thani, Nakhon Ratchasima, Ubon Ratchathani, Surat Thani, Phuket, Songkhla, and Trang. There is also a lab at the medical school that can test for drug allergy genes as well. Hospitals interested in using the digital platform “Pukphan” can contact for further details at Institute of Medical Biosciences Genomics Medical Center Tel. 02 951 0000 ext. 98095, 98096 or website and 14 medical science centers nationwide.
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