Image source: Free Times
Adult exposure to cigarette smoke is widely recognized as a risk factor for type 2 diabetes. Previous studies have found that adult smokers are 30% to 40% more likely to develop type 2 diabetes compared to non-smokers.
However, some researchers said it is still unclear how early exposure to tobacco smoke affects the development of type 2 diabetes and whether this association differs depending on genetic susceptibility to type 2 diabetes.
The results of a preliminary study were published at the American Heart Association’s Epidemiology and Prevention Lifestyle and Cardiometabolic Sciences conference in March of this year. Exposure to tobacco smoke during fetal life and starting smoking in childhood or adolescence are strongly associated with the development of type 2 diabetes in adulthood, according to a UK Biobank study of nearly half a million adults. , particularly among those with diabetes at high genetic risk for type 2 diabetes.
In the study, researchers examined data from nearly 500,000 adults from the UK Biobank to assess tobacco exposure during fetal life and initiation of cigarette smoking in childhood (5-14 years) or adolescence (15-17 years). 2 diabetes. The polygenic risk score for type 2 diabetes was used to evaluate the possible interactive and joint effects of early tobacco exposure and genetic predisposition on the development of type 2 diabetes.
Participants with a genetic predisposition to type 2 diabetes and who began smoking during childhood or adolescence had the highest risk of developing type 2 diabetes among people who had been exposed to tobacco before birth or had started smoking during childhood or adolescence.
Compared to people who have never smoked, exposure to tobacco smoke during fetal life is associated with a 22% increased risk of developing type 2 diabetes. Those who start smoking as a child have double the risk of develop type 2 diabetes, and those who start smoking as adolescents have a 57% higher risk. People who start smoking as adults had a 33% higher risk.
People who were exposed to tobacco smoke during fetal life, who started smoking during childhood or adolescence, and who had a high genetic risk score were more likely to develop type 2 diabetes than participants who had not been exposed to tobacco smoke in early childhood and had a low genetic risk score. genetic risk score for type 2 diabetes Risk increases were 330%, 639%, and 427%, respectively.
Cigarette smoke contains 6,000 chemicals, hundreds of toxic substances and dozens of substances recognized as level 1 carcinogens. The author urges smokers not to underestimate the dangers of smoking indoors. According to research, cigarette smoking may increase the risk of fetal diabetes. If you must smoke, be sure to go to a smoking room, balcony and other well-ventilated places. Don’t underestimate him. The harm of cigarettes to your family.
文章來源: Exposure to tobacco before birth significantly increases the risk of type 2 diabetes in adults | American Heart Association
#unborn #fetuses #develop #diabetes #grow
