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Woman’s Dreams Shattered by Rare Skin Reaction to Antibiotics
Severe Stevens-Johnson Syndrome Causes Permanent Damage and Vision Loss
Sasinan Chuenrosang, a 31-year-old woman from Thailand, visited a hospital in Bangkok on June 18 with symptoms of sore throat and bloodshot eyes. She was diagnosed with tonsillitis and prescribed an antibiotic called Ceftriaxone. However, her symptoms worsened, and she was prescribed the same antibiotic twice more, despite her condition deteriorating.
Chuenrosang’s symptoms worsened, and she developed a rash on her face and body, lost the sight in her left eye, and experienced blurred vision, a swollen mouth, and difficulty walking. She was transferred to the intensive care unit, where she was administered the same antibiotic again. Afterward, she felt dizzy, and her right eye began to blur and lose sensation.
Chuenrosang was hospitalized in the intensive care unit for seven days and then transferred to another hospital, where she was diagnosed with severe Stevens-Johnson syndrome. Stevens-Johnson syndrome is a rare disease that occurs on the skin and mucous membranes as a reaction to drugs or infections.
Chuenrosang is still receiving treatment to this day. She had to cut off her long hair due to the rash and has cuts around her eyes, mouth, forehead, and cheeks. She wraps gauze around her neck to wipe away the blood and pus that is dripping from her face. She is also looking for an ophthalmologist to help her regain her vision and is desperately hoping to return to her normal life.
“The pain was so bad I thought I was going to die. My whole body felt like it was on fire and it was hot and stinging, and there are no words to describe what it felt like,” Chuenrosang said. “This disease shattered my dreams.”
Thailand’s deputy public health minister said the government was investigating whether Chuenrosang’s treatment was “consistent with medical practice.”
What is Stevens-Johnson Syndrome?
Stevens-Johnson syndrome is a rare disease that occurs on the skin and mucous membranes as a reaction to drugs or infections. It starts with flu-like symptoms, then a painful rash spreads and blisters appear. Then, the outermost layer of the infected skin dies and peels off, and it begins to heal. If it is a drug reaction, the reaction to the drug can occur while taking the drug or for up to two weeks after stopping taking it.
Symptoms may include fever, sore mouth and throat, fatigue, and burning eyes 1-3 days before the rash appears. As the disease progresses, other symptoms may include unexplained widespread skin pain, a red or purple rash, blisters on the skin and mucous membranes of the mouth, nose, eyes, and genitals, and peeling of the skin within a few days after the blisters appear.
Complications of Stevens-Johnson Syndrome
According to the Mayo Clinic in the United States, Stevens-Johnson syndrome can cause a variety of complications, including:
* Dehydration: Fluids are lost in the abraded area, and inflammation in the mouth and throat makes it difficult to drink water.
* Blood infection (sepsis): Bacteria from the infection can enter the bloodstream and spread throughout the body.
* Eye problems: The rash can cause eye inflammation, dry eyes, light sensitivity, and in severe cases, visual impairment and, in rare cases, blindness.
* Lung invasion: An emergency situation may occur where the lungs cannot supply enough oxygen to the blood.
* Permanent skin damage: As the skin regenerates, it may appear bumpy or abnormally pigmented (dyspigmentation). If the skin problem persists, hair loss may occur, and fingernails and toenails may not grow as well as they used to.
Stevens-Johnson syndrome is a rare and unpredictable disease. Factors that increase the risk of developing the disease are known to include HIV infection, weakened immune system, cancer, history or family history of Stevens-Johnson syndrome, and genetic factors. Stevens-Johnson syndrome is a disease that requires immediate treatment, so if you have any suspicious symptoms, you should visit a hospital immediately.
