Studies ⁣Examine Mouthwash, Alcohol and Cancer Risk

‌Updated May 30, 2025

Several studies have explored the potential link‌ between mouthwash use and cancer risk, specifically focusing on oral cancer.While the evidence remains inconclusive, certain findings suggest a possible association, particularly with frequent use of alcohol-containing mouthwash.

A 2007 study by Guha et al.,‍ a pooled analysis of nine case-control studies, indicated a slight increase⁤ in the risk ⁤of ⁤head and neck cancers among users of high-alcohol-content mouthwash. This raised initial concerns about the ingredients in certain oral hygiene products.

McCullough & Farah’s 2008 literature review on alcohol-containing mouthwashes also pointed to a potential link between frequent use and an increased risk of oral cancer. However, the authors emphasized that the evidence was not conclusive and called for further inquiry⁢ into the matter.

Lacruz et al.‍ (2018) conducted a systematic review and meta-analysis, revealing a weak ⁣but statistically significant association between frequent mouthwash use ‍(more than twice a day) and oral cancer risk. This finding added to the existing ​body of evidence suggesting⁣ a possible correlation.

In contrast, a 2012 meta-analysis of epidemiological studies ⁣by Gandini et al. found insufficient ​evidence to establish ⁣a clear link between mouthwash⁢ use and cancer risk. ‍The researchers noted that while a ​definitive ⁣link couldn’t be established, ⁣the possibility of a risk could not be entirely ruled out.

What’s next

Further research is needed to determine the definitive relationship between frequent mouthwash use,the ​presence of alcohol,and the potential growth‍ of‍ oral cancers. Future studies should focus on specific ingredients and usage patterns⁣ to ⁤clarify any potential risks.