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Obesity Genes: New Research Reshapes Weight Risk

November 3, 2025 Jennifer Chen Health
News Context
At a glance
  • Okay, ⁣here's a breakdown of the‍ abbreviations used in the provided⁣ text, along with thier full forms:
  • * BMI: Body Mass ‍Index * ‍ PGS: Polygenic Scores * KB: (Likely refers to the UK biobank, given the context of 50,000 participants) * ‍ PTV: Protein-Truncating...
Original source: news-medical.net

Okay, ⁣here’s a breakdown of the‍ abbreviations used in the provided⁣ text, along with thier full forms:

* BMI: Body Mass ‍Index
* ‍ PGS: Polygenic Scores
* KB: (Likely refers to the UK biobank, given the context of 50,000 participants)
* ‍ PTV: Protein-Truncating Variant
* GTEx: Genotype-Tissue Expression project
* IMPC: ⁤ International Mouse Phenotyping consortium
* CMDKP: Common⁤ Metabolic Diseases Knowledge Portal
* MC4R: Melanocortin 4 Receptor
* BSN: Bassoon Presynaptic Cytomatrix Protein
* PCSK1: Proprotein Convertase Subtilisin/Kexin Type 1
*⁤ RIF1: Replication Timing Regulatory Factor 1
* YLPM1: YLP ⁢Motif Containing‍ 1
* GIGYF1: ⁣ Grb10 Interacting ⁢Protein 1
* SLC5A3: Solute Carrier Family 5 Member 3
* ⁢ GRM7: Glutamate Metabotropic receptor 7
* SLTM: SAFB-like Transcription Modulator
* APBA1: Amyloid Beta Precursor Protein ⁤Binding Family Member 1
* WHICH: (Likely a statistical method or software used for mediation analysis, but the full form isn’t explicitly stated)
* ⁣ GERD: Gastroesophageal Reflux Disease
* PheWAS: Phenome-Wide Association Study

I hope this ⁢is⁤ helpful! ⁢Let me know if you have any other questions.

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Adipose, Body Mass Index, brain, diabetes, Gastroesophageal reflux disease, Gene, Genes, Genetic, heart, heart failure, Metabolic Disease, obesity, protein, Proteomics, Receptor, Research, type 2 diabetes

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