There is a corona treatment that can defeat all mutated viruses by just spraying it into the nose

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[인사이트] Reporter Im Ki-soo = There is a corona treatment that defeats all mutated viruses just by spraying it into the nose.

It has been confirmed that the new corona nasal spray treatment has superior performance than the currently used antibody treatment.

Regardless of the type of mutated virus, it shows a high therapeutic effect, raising expectations from people around the world.

Researchers at Northwestern University, University of Washington, and University of Washington Medical School announced that they have developed a new protein-based antiviral nasal spray treatment and have started Phase 1 clinical trials in humans.

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The researchers computerized a protein that inhibits the ability of the coronavirus to penetrate human cells, purified it in the laboratory, and made it into a spray.

In preclinical studies on animals, it was found that the virus neutralizing ability was similar to or greater than that of the antibody treatment currently in use with US Food and Drug Administration (FDA) approval.

In particular, it worked for all mutations, including delta and omicron.

Previously, the research team used a supercomputer to design a protein that can stick to the vulnerable part of the surface of the spike protein used when the Corona 19 virus penetrates the human body, and published a paper in the international academic journal ‘Science’ in 2020.

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The antiviral protein blocks the binding of the spike protein to the ACE2 receptor for penetration into the body while maintaining the binding to the spike protein of the Corona 19 virus.

In particular, the mini-binder developed by the research team maintained its effectiveness even in the case of COVID-19 micron mutation.

The results of this study were published in the international scientific journal ‘Science Translational Medicine’ on the 12th (local time).

Meanwhile, in Korea, interest in spray-type medicines that are sprayed into the nose has recently been attracting attention.

SK Bioscience has also recently started developing a nasal COVID-19 drug with the International Aids Vaccine Promotion Agency (IAVI) and the University of Washington Antigen Design Research Institute (IPD).