Major risk factors such as hypertriglyceridemia and abdominal obesity
The risk of developing a new metabolic syndrome is more than doubled
A study has been published showing an increased risk of gout in young men with metabolic syndrome.
Metabolic syndrome is a case of having three or more hypertension, hyperglycemia, hypertriglyceridemia, low high-density lipoprotein cholesterol, and abdominal obesity, and is known as a risk factor for diabetes, fatty liver, and cardiovascular disease.
Professor Eun Young-hee from Sungkyunkwan University College of Medicine (Department of Rheumatology, Kangbuk Samsung Hospital), Professor Lee Jae-jun (Department of Rheumatology, Samsung Hospital Seoul), and Professor Kim Hyung-jin (International Medical Center Samsung Hospital Seoul ) followed up for 7.4 years.
As a result, people with metabolic syndrome had a 2.4 times greater risk of developing gout than those without metabolic syndrome. Among the metabolic syndrome factors, hypertriglyceridemia and abdominal obesity were particularly correlated with gout, and the more metabolic syndrome factors there were, the higher the risk of gout.
The research team also carried out a follow-up study to see if changes in metabolic syndrome affect the incidence of gout.
Analysis of 1.29 million men aged 20 to 39 who took part in three consecutive health checks every two years found that the risk of gout was almost four times higher in those with chronic metabolic syndrome compared to the those without metabolic syndrome. When a person without metabolic syndrome developed metabolic syndrome, the risk of gout increased more than twice, and conversely, when a person with metabolic syndrome recovered from metabolic syndrome, the risk of gout was reduced by almost half.
Professor Eun Young-hee said, “It is well known that the number of gout patients in young men is increasing rapidly, but there have been few studies on the risk factors that cause gout.” These studies show that metabolic syndrome is an important risk factor for gout in young men. This suggests that active management of metabolic syndrome is essential for the prevention of gout.”
This study and American Journal of Rheumatology was published on
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