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Older people with hydrocephalus should suspect Parkinson’s disease if they kick or move slowly while sleeping

A case of a patient diagnosed with normal pressure hydrocephalus with Parkinson’s disease was found in Korea.

In general, it has been known that normal pressure hydrocephalus is not accompanied by Parkinson’s disease. A team led by Professor Park Young-ho of the Department of Neurology at Seoul National University Bundang Hospital recently reported a case with Parkinson’s disease in a patient with normal pressure hydrocephalus.

Professor Park Young-ho said, “Normal pressure hydrocephalus is a relatively common disease that can be seen in two out of 100 people over 70 years of age. The symptoms improved after taking Parkinson’s drugs along with cerebrospinal fluid drainage.”

(Picture above) Compared to the left normal brain, it can be seen that the ventricles are dilated due to the excessive accumulation of cerebrospinal fluid in the right normal pressure hydrocephalus. (Picture below) In the brain of the right Parkinson’s disease patient, the response in the basal ganglia is weaker than in the left normal brain. (Photo = Seoul National University Bundang Hospital)

If too much cerebrospinal fluid is produced or absorbed well, it gradually accumulates. This condition is hydrocephalus. When hydrocephalus occurs even when the cerebrospinal fluid pressure is in the normal range, it is called normal pressure hydrocephalus. Hydrocephalus is a condition in which excessive accumulation of cerebrospinal fluid compresses brain tissue, resulting in symptoms such as gait and urination disorders and memory loss. Although symptoms are confused with Parkinson’s disease, hydrocephalus can be improved with surgical treatment.

If too much cerebrospinal fluid is produced or absorbed well, hydrocephalus, which accumulates, compresses the brain tissue, causing symptoms such as gait and urination difficulties and memory loss. Symptoms are similar to Parkinson’s disease, but hydrocephalus can be improved with surgery. REM sleep behavior disorder is a symptom in which the contents of a dream are translated into actual actions because the muscle tension is not lowered abnormally during sleep. Dysfunction refers to slow action.

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Professor Park explained, “Even if you suffer from normal pressure hydrocephalus, if you have REM sleep behavior disorder or noticeably slow movements, it may be accompanied by Parkinson’s disease.”

Meanwhile, the clinical research results, including cases and treatment of the patient, were published in the July issue of Neurology, a journal of the American Neurological Association.