Fecal Transplant from Mother Leads Canadian Man to Develop Menopausal Symptoms
Recently, a peculiar case of a man experiencing menopausal symptoms after receiving a fecal transplant from his mother has garnered attention. Charlie Curtis, a resident of Toronto, Canada, had undergone the transplant at home to alleviate symptoms of Crohn’s disease, but instead found himself exhibiting symptoms typically associated with menopausal women.
The Journey of Charlie Curtis
Charlie’s medical history dates back to his diagnosis of ulcerative colitis at the age of eighteen, a condition marked by chronic inflammation of the large intestine. Despite ongoing medical treatment, his condition worsened, ultimately leading to a diagnosis of Crohn’s disease, a chronic inflammatory bowel disease.
Desperate for a solution, Charlie’s mother sought advice from the Digestive Disease Center in Sydney, Australia, which recommended a fecal transplant using the mother’s feces to restore microbial balance in Charlie’s intestines.
Following the transplant, Charlie’s health improved significantly, and he was able to resume a normal life. However, he experienced unexpected side effects in the form of menopausal symptoms, including sweating, flushing, and mood swings, mirroring his mother’s symptoms at the time of the transplant.
Potential Implications of Fecal Transplantation
The case has prompted speculation about the possibility of maternal hormones being transferred through fecal transplantation, causing such unexpected symptoms in the recipient. Dr. Thomas Borody, Director of the Digestive Diseases Centre, acknowledged the potential transfer of high levels of hormones through fecal transplant, underscoring the need for further research in this area.
While Charlie expressed satisfaction with the overall outcome of the procedure, he acknowledged the unforeseen nature of the side effects. His mother, in a 2011 interview, reflected on the drastic improvement in Charlie’s quality of life post-transplant, highlighting the transformative impact of the procedure.
The case sheds light on the unexplored possibilities and potential risks associated with fecal microbiota transplantation, emphasizing the need for further research and caution in its application. As medical science continues to evolve, compelling cases like Charlie’s offer valuable insights into the complexities of biological interventions and their far-reaching effects.
Menopausal symptoms after direct transplantation of faeces given by the mother… Possibility of transplantation of maternal hormones too
Entered 2023.11.17 13:30 Views 120 Entered 2023.11.17 13:30 Modified 2023.11.17 13:47 Views 120
The story of a man who had menopausal symptoms with his mother after receiving a ‘self’ transplant from his mother’s faeces was presented. [상단 사진=사연의 어머니와 아들 ‘더선(The Sun)’ 보도내용 캡처 / 하단= 분변이식 모형도 게티이미지뱅크 편집 ]The story of a man who had menopausal symptoms with his mother after receiving a ‘self’ transplant from his mother’s faeces was presented.
According to a recent report by the British media ‘The Sun’, a man from Toronto, Canada called Charlie Curtis disappeared from the symptoms of Crohn’s disease after a faeces transplant given by his mother at home, but showed other symptoms that he had These were menopausal symptoms that come to menopausal women. How could this happen?
Charlie was diagnosed with ulcerative colitis at the age of eighteen. Ulcerative colitis is a chronic inflammatory disease of unknown cause that affects the large intestine. Symptoms include watery stools containing blood or diarrhea several times a day, severe abdominal pain, dehydration, anaemia, fever, loss of appetite, weight loss and fatigue.
He later found out he had Crohn’s disease. Crohn’s disease is a chronic inflammatory bowel disease that can occur anywhere in the digestive tract, from the mouth to the anus.
Despite taking medication to control his symptoms, Charlie had to go to the bathroom up to 40 times a day. In two months, I lost 29.5kg of weight, lost a lot of blood, and lived in pain almost every day. Charlie became so debilitated with symptoms such as diarrhoea, fatigue, abdominal pain, weight loss, and fever that he had to leave college and was admitted to hospital.
Fecal transplantation, the transfer of healthy feces into the patient’s intestines to restore microbial balance
Desperate to restore her son’s life, Charlie’s mother contacted the Digestive Disease Center in Sydney, Australia, which specializes in treating inflammatory bowel disease, and its director, Thomas Borody, suggested a fecal transplant using the mother’s feces.
Faecal microbiota transplantation (FMT) is a technology that restores the balance of the intestinal microbial community by transferring healthy feces from a donor to the patient’s intestines. In other words, micro-organisms present in the faeces of a healthy individual are transplanted into the intestines of an infected person. It is attracting attention as the most effective treatment for patients suffering from Clostridium difficile infection. Research results show that it is also effective for ulcerative colitis and irritable bowel syndrome. There are ways to insert it through the anus using an endoscope or enema device, insert it through the mouth or nose using an upper endoscope, or give a frozen frozen capsule orally.
Fecal transplant or fecal material transplant (FMT). Laboratory tubes containing faecal micro-organisms to treat persistent digestive diseases such as clostridial bacterial infections *Images are for illustrative purposes only [사진=게티이미지뱅크]However, since fecal microbiota transplantation is only approved for Clostridium difficile infection in the United States and Canada, Charlie and his mother decided to perform it at home.
After testing his mother’s faeces for infections and diseases, it was confirmed that there were no problems in December 2008, and Charlie began receiving implants by inserting them into the anus. For the first month, I transplanted every day and gradually reduced the frequency.
After having transplants once a month for three and a half years, Charlie felt almost back to normal, and was featured in the 2019 documentary ‘Designer $hit’ (the director, who suffered from ulcerative colitis for almost 10 years), discussing the faecal microbiota transplant procedure He also appeared in ‘Documentary about his journey to discover the possibility of treatment’, but at the time this documentary was filmed, he had no symptoms and was not take any medicine.
A mother’s menopausal symptoms, such as sweating and facial flushing, appear on her son
But there was one strange thing. During the transplant, Charlie experienced unexpected side effects. Symptoms included excessive sweating, facial flushing, and severe mood swings, which were almost identical to his mother’s symptoms at the time. His mother was going through menopause, and Charlie was experiencing the same symptoms.
It is not clear whether his symptoms were caused by his mother’s faeces. However, Borody, of the Digestive Diseases Centre, said it was possible that Charlie was absorbing hormones from his mother’s faeces because “high levels of hormones can be transferred” when faeces are transplanted.
Charlie said he doesn’t regret his decision to have a fecal transplant for a second. He said he felt like he had a new digestive system and a new body, and that he had never felt so healthy in his life.
In a 2011 interview with the Canadian Daily Star Toronto, his mother said, “Charlie’s previous life consisted of lying in bed or tied to the bathroom, pooping bloody stools, his joints were so swollen he could barely walk , and would lie on the bathroom floor in pain, “I used to cry,” she recalled. But he added, “Now I’m back at school and I have a girlfriend.”
If you are new to faecal microbiota transplantation, the concept may be surprising. However, fecal transplantation has been found to be effective in treating certain diseases, including inflammatory bowel disease. However, if an individual tries an unproven method, various side effects can occur, so it has to be performed in a hospital using a proven method.
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