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The Scent of Ripe Fruit: A Potential Cancer Cell Inhibitor

Research results have been published showing that the scent of ripe fruit has the effect of inhibiting the proliferation of cancer cells. [사진: 셔터스톡]

[디지털투데이 AI리포터] Research results have been published showing that the scent of ripe fruit has the effect of inhibiting the proliferation of cancer cells.

According to the Japanese newspaper Gigagene, on the 4th (local time), a research team led by Ananda Sanka Ray of the University of California, USA, confirmed that a substance called “diacetyl” acts as a histone deacetylase (HDAC) inhibitor. . Diacetyl is a volatile compound released by yeast during the fruit fermentation process and is sometimes used to flavor popcorn, etc. with butter or as a flavoring agent in electronic cigarettes.

The research team exposed fruit flies and mice to diacetyl vapor for five days. As a result, extensive changes in gene expression occurred in various tissues, including cells, lungs, and antennae of fruit flies and mice. Notably, it was confirmed that the growth of cultured human neuroblastoma cells stopped when exposed to diacetyl vapor.

“We made the important discovery that some volatile compounds released by microorganisms and foods can modify the epigenetic state of neurons and other eukaryotic cells,” explains Ray.

The results showed that diacetyl vapor inhibits the proliferation of cancer cells, but direct inhalation of the vapor is not the correct method. Direct inhalation can cause changes in airway cells and obstructive bronchitis. Based on this study, the research team is conducting research to find other volatile substances that cause changes in gene expression.

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