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The Long-lasting Traces of Nicotine: Detecting Addictive Substance in Hair for Years

Hair Testing Reveals Traces of Nicotine for Years, Study Shows

When it comes to nicotine addiction, new research suggests its presence can be detected in hair follicles for an extended period of time.

The addictive properties of nicotine, primarily found in cigarettes, are well-known. Once inhaled, nicotine enters the bloodstream and is metabolized into cotinine in the liver. Cotinine, the main nicotine metabolite, is used to determine the presence of nicotine in the body. It has been found to exhibit high sensitivity and a longer half-life compared to other nicotine breakdown products.

Stay Impacted: Nicotine Traces in Urine, Blood, Saliva, and Hair

According to information sourced from the reputed American health information media outlet, ‘Healthline’, the duration nicotine remains in the body can vary based on smoking methods and frequency. Nicotine has a half-life of about 2 hours, while cotinine, with a longer half-life of approximately 16 hours, is utilized as a major biomarker for assessing exposure to smoking or cigarette smoke. Half-life refers to the time taken for a substance’s quantity to decrease to half its original amount.

Urine Test: Urinary cotinine concentration is typically 4 to 6 times higher than in plasma or saliva. In a urine test conducted on individuals preparing for bariatric surgery in 2016, cotinine levels displayed high sensitivity and specificity for detecting smoking in the last 72 hours. However, results may vary depending on smoking frequency and quantity.

According to the University of Rochester Medical Center, urinary cotinine levels begin returning to normal approximately 7 to 10 days after the last cigarette smoked. For frequent smokers, it can take up to three weeks for cotinine to completely leave the body. Notably, a 2020 study revealed the detection of cotinine in urine for at least eight weeks.

Blood Test: Compared to urine, the concentrations of cotinine in saliva and blood are lower. Nicotine can be detected in the bloodstream as early as one hour after exposure. A peer-reviewed article from the University of Illinois College of Medicine in 2017 reported cotinine’s traceability in the blood for up to 10 days after quitting smoking. However, this timeframe may vary based on genetic factors and nicotine exposure. Blood tests show lower sensitivity in comparison to urine tests.

Saliva Test: Nicotine remains present in saliva for roughly 24 hours, while cotinine can be detected up to 7 days after the last cigarette, and even up to 14 days in heavy smokers.

Hair Test: A literature review published in 2021 established the extended timeframe in which traces of nicotine can be observed in hair follicles, ranging from weeks to months and even years after exposure. Hair tests can also indicate indirect or environmental tobacco smoke exposure. However, this testing method is not as commonly used as urine, saliva, or blood tests.

Factors Affecting Duration: Individual Variability

Multiple factors contribute to the duration nicotine remains in the body, varying from person to person. A 2010 research study identified several influential factors, including cigarette smoking and exposure to nicotine products, smoking frequency and exposure, genetic factors, liver function, age, diet and medication use, gender and hormonal differences, kidney function, and metabolite presence over time.

Detoxification: Clearing the Body of Nicotine

The most effective way to eliminate nicotine from the body is to quit smoking and minimize exposure to nicotine products. Methods to accelerate the elimination process involve increased water consumption, regular exercise, and consumption of antioxidant-rich foods. Drinking more water leads to increased nicotine excretion through urine, while exercise boosts metabolic rates and aids nicotine elimination through sweat. Antioxidants contribute to a faster metabolism as well.

Nicotine Liberation: Associated Side Effects

Nicotine, the addictive compound found in cigarettes, can cause withdrawal symptoms when usage is ceased due to tolerance and dependence. These symptoms may include fatigue, lack of concentration, headaches, constipation, nausea, diarrhea, irritability, increased hunger, anxiety, depression, and insomnia. The severity and duration of withdrawal symptoms vary depending on various factors, such as smoking duration, the type of product used, and daily consumption.

Over-the-counter or prescription medications can assist in managing these symptoms. Additionally, nicotine replacement therapies, such as smoking cessation patches, are commonly employed to alleviate withdrawal discomfort.

Highly addictive traces of nicotine can be detected in hair for up to several years.

Entered 2023.11.07 05:40 Views 3,056 Entered 2023.11.07 05:40 Modified 2023.11.06 18:51 Views 3,056

When you smoke or inhale tobacco smoke indirectly, nicotine is absorbed into your bloodstream. [사진=게티이미지뱅크]When you smoke or inhale tobacco smoke indirectly, nicotine is absorbed into your bloodstream. Nicotine is an addictive substance found mainly in cigarettes, and when it enters the body, most of it is metabolized in the liver and converted into cotinine. You can check if you have been exposed to nicotine by testing for cotinine, the main metabolite of nicotine. Cotinine is known to have high sensitivity and a long half-life compared to other nicotine breakdown products.

Let’s find out how long nicotine can stay in the body based on information presented by the American health information media ‘Healthline’.

Traces of nicotine in urine, blood, saliva and hair

The length of time nicotine stays in the body varies depending on the method of smoking and how often. The half-life is about 2 hours. On the other hand, the half-life of cotinine is longer, around 16 hours. Therefore, it is used as a major biomarker in the evaluation of smoking or cigarette smoke exposure compared to nicotine, which has a shorter half-life. A half-life is the time it takes for an amount of a substance to become half of its original amount.

urine test = Urinary cotinine concentration is about 4 to 6 times higher than the concentration in plasma or saliva. In 2016, cotinine levels were checked by urine tests in people preparing for bariatric surgery, and found to have high sensitivity and specificity for smoking in at least the last 72 hours. However, results may vary depending on the frequency and amount of smoking.

According to the University of Rochester Medical Center, urinary cotinine levels begin to return to normal about 7 to 10 days after the last cigarette smoked. If you are a frequent smoker, it can take up to three weeks to remove cotinine from your body. Meanwhile, a study conducted in 2020 found that cotinine can be detected in urine for at least eight weeks.

blood test = Saliva and blood have lower concentrations of cotinine than urine. Nicotine can appear in the bloodstream about an hour after exposure. According to a 2017 peer-reviewed article from the University of Illinois College of Medicine, cotinine can be detected in the blood for up to 10 days after quitting smoking. The length of time that cotinine can be detected in the blood can vary depending on genetic factors and the amount of nicotine exposure. It has a lower sensitivity than a urine test.

saliva test = Nicotine stays in saliva for about 24 hours. Cotinine can be detected up to 7 days after the last cigarette, and up to 14 days in heavy smokers.

hair test = Traces of nicotine can be found in hair follicles up to weeks, months, and even years after the last exposure, according to a literature review published in 2021. Hair tests can also reflect indirect or environmental exposure to tobacco smoke. It is not used as often as urine, saliva, or blood tests.

What factors influence how long you stay?

Factors that affect how long nicotine stays in the body vary from person to person. According to research results published in 2010, factors such as △ cigarette smoking and exposure to types of nicotine products △ smoking frequency and exposure △ genetic factors △ liver function △ age △ diet and medication use △ gender and hormonal differences △ kidney function and how long its metabolites are found in the body.

How to get rid of nicotine from the body?

The best way to get rid of nicotine from your body is to stop smoking and avoid contact with nicotine products. Ways to speed up the nicotine elimination process include drinking water, exercising, and eating foods rich in antioxidants. When you drink more water, more nicotine is excreted through urine, and exercise not only increases the body’s metabolic rate, but also excretes nicotine when you sweat. Antioxidants can also help speed up your metabolism.

Side effects that can occur when nicotine is released

Nicotine is the main addictive ingredient found in cigarettes. Due to tolerance and dependence, cessation can lead to withdrawal symptoms such as fatigue, lack of concentration, headaches, constipation, nausea, diarrhea, irritability, increased hunger, anxiety, depression and insomnia. Withdrawal symptoms are usually most severe in the first few hours after the last cigarette and often decrease in severity after about three days. The symptoms or how long they appear depend on a variety of factors, including how long you’ve been smoking, the type of product you used, and how much you smoke each day.

Over-the-counter or prescription medications can help, and nicotine replacement therapies (NRTs), such as smoking cessation patches, are also used to ease withdrawal symptoms.

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