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The Science Behind Mole Formation: Genetics, Ultraviolet Rays, Hormones, Aging, and More

There are 5 main reasons for the appearance of moles: genetics, ultraviolet rays, hormones, medications, aging, etc.

Posted 2024.02.10 07:05 Posted 2024.02.10 07:05 Modified 2024.02.09 21:07 Views 0

Why do moles appear? Since when did grains become incorporated into my body? [사진=클립아트코리아]There are times when you notice something that wasn’t visible before. When did it happen? Before you know it, spots appear on your neck, shoulders, arms and face. Without even realizing it, ‘these’ seem to have come together and stand out on my skin. Why do moles form with grains stuck there?

“These” are skin pigments that are deposited on the skin and reveal their presence as spots. In medical terms the mole is called a “small pigmented nevus”. It is a nevus made up of point cells and its scientific name is nevus. Unless you are born with a mole or Mongolian spot, most birthmarks appear one by one during the first five years of life and generally form during childhood and early adulthood.

Moles form on the skin due to clusters of melanocytes. Melanocytes are cells that produce the pigment melanin and are responsible for giving color to the skin. Moles form due to changes in the melanin pigment in the mucosal layer beneath each layer of the skin’s epidermis. Moles are usually caused by the accumulation of pigment in the dermis, one of the two layers of the dermis and epidermis, and can be said to be a type of skin deformity.

Depending on the tissue, it varies from thin areas in the epidermis to very deep-rooted areas. It appears most commonly in our bodies as dark brown or black, but surprisingly it also comes in a variety of colors. If there is a problem with the blood vessels, the mole may appear red (known as a cherry haemangioma), if the mole is deep it may appear blue, and if the pigment melanin is not being produced it may appear white.

Moles can appear anywhere on the skin. They can fly anywhere, including the arms and legs, back, face and neck, scalp, head, and chest, but appear relatively rarely on the soles of the feet, palms of the hands, and between the fingers and of the feet.

Were the moles on my body meant to be there? Why does this happen? The major influence appears to be genetic. Research on moles has shown that mutations in the BRAF gene promote mole growth. Like freckles, moles are more common in people with fair skin. Genetic influences determine not only the number of moles, but also their location. Atypical moles, or dysplastic nevi, are usually caused by heredity. These types of moles are said to run in families and increase the risk of developing skin cancer.

The interesting thing is that the characteristics of moles can vary depending on gender. One study found that women tend to have more moles on their lower bodies than men. It is said to be influenced by the genetic composition of each sex and that moles on the lower part of a woman’s body may be protruding or flat, and hair may grow on top of the moles.

As we all know, UV exposure also affects moles. Excessive exposure to ultraviolet rays, especially during childhood, can cause spots to appear later in life. This is because the sun damages the DNA of skin cells, causing them to mutate. This causes the melanocytes to divide uncontrollably and appear as spots. This is probably why it is said to avoid sunlight to prevent blemishes.

Hormones can also affect the number of moles a person has. Hormonal fluctuations, due for example to pregnancy, menopause or puberty, can cause the appearance of new spots. Due to hormonal changes, the mole may become darker or larger. Research continues into how hormones affect moles.

Skin damage due to exposure to sunlight can occur in childhood and only appear as a side effect in later life. As we age, the skin’s ability to repair itself decreases, subsequently leaving blemishes. Conversely, some spots disappear due to skin changes as we age. If a noticeably new mole appears, you may need to see a dermatologist.

If you take certain medications, this is also one of the causes of the appearance of moles. Moles appear when the body reacts to the use of certain medications, including common ones such as antidepressants, by suppressing the immune system. Although these drugs do not cause suppression of the immune system, some skin conditions, such as eczema, make the skin’s immune cells more sensitive, which leads to the development of moles.

How to prevent the formation of moles? The most important thing is to block sunlight! It’s a good idea to get into the habit of applying sunscreen every day, wearing clothing that protects your body from the sun, and avoiding tanning.

In general it is not necessary to remove it unless it is a cosmetic problem, but if △it becomes larger, △the number suddenly increases, △itchy and painful symptoms appear, △the color becomes abnormal, △inflammation occurs, or △an ulcer occurs, a hospital visit is required.

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